Whether to apply row-scaling on the matrix affects the clustering step in consensus partitioning, which might give different partition results on the samples. For the expression matrices, we recommend to scale rows because the more interesting thing is the subgrouping where genes show similar expression patterns in the sense of e.g. genes showing consistent up-regulation in the subgroups. If the rows are not scaled, the partitions are more generally affected by highly expressed genes.

In this analysis, we performed cola analysis on Golub Leukemia dataset by applying row-scaling on the matrix and not. The choice of row-scaling can be tuned by setting scale_rows to TRUE or FALSE in run_all_consensus_partition_methods() or consensus_partition() function.

For the partition methods hclust, kmeans, skmeans, pam and mclust, z-score scaling is applied as \((x-\mu)/\sigma\), and for NMF, the “min-max” scalling is applied as (x - min)/(max - min).

Consensus heatmaps for two subgroups

Figure 1A and 1B (switching the tabs in the following figure) illustrate consensus heatmaps for two-group classification with or without row-scaling. Table 1 lists the stability of consensus partition under different methods (measured by 1-PAC scores):

Table 1. 1-PAC scores of the consensus partitioning under each method (k = 2). Partitions with 1-PAC > 0.9 (numbers in red) are considered as stable partitions.
Rows are scaled Rows are unscaled
ATC:skmeans 1 0.67
ATC:kmeans 1 0.66
ATC:NMF 0.97 0.55
SD:skmeans 0.62 1
CV:skmeans 0.63 1
MAD:skmeans 0.64 1
SD:kmeans 0.66 1
CV:kmeans 0.65 1
MAD:kmeans 0.62 1
CV:mclust 0.49 0.98
MAD:mclust 0.82 0.96
SD:mclust 0.37 0.74
CV:NMF 0.63 0.68
MAD:NMF 0.68 0.65
SD:NMF 0.63 0.63
SD:pam 0.55 0.62
MAD:pam 0.65 0.58
CV:pam 0.55 0.55
MAD:hclust 0.23 0.53
ATC:pam 0.6 0.51
SD:hclust 0.24 0.44
ATC:hclust 0.57 0.4
CV:hclust 0.21 0.38
ATC:mclust 0.36 0.36



Rows are scaled

Figure 1A. Consensus heatmaps with two subgroups. Matrix rows are scaled.

Figure 1A. Consensus heatmaps with two subgroups. Matrix rows are scaled.

Rows are unscaled

Figure 1B. Consensus heatmaps with two subgroups. Matrix rows are unscaled.

Figure 1B. Consensus heatmaps with two subgroups. Matrix rows are unscaled.

A quick look shows the partitioning results are different when rows are scaled and not. We will discuss with more details in the next section.

Classification from all methods

Figure 2 puts classifications from all 24 methods together as well as one clinical annotation. The annotation ALL.AML tells whether the patient (the sample) had ALL or AML. The lightness of the main heatmap corresponds to the silhouette scores for samples measured in each partitioning method. With lighter color, the less stable for the sample to stay in its group.

When the matrix rows are scaled (top heatmap in Figure 2), there are two major sets of different classifications where methods integrated with mclust, kmeans, and NMF classify samples into two groups where one group mainly contains AML samples. Other methods integrated with ATC, skmeans and pam generate classifications where a subset of ALL samples move to the same group of AML samples. Although there are two different two-group classifications, the samples that have different classifications among methods generally have lower silhouette scores in the corresponding consensus partition runs ( i.e. the colors in the heatmap are lighter), which means, they are less confident samples for the classifications and different partition methods might classify them into different groups.

When the matrix are not scaled (bottom heatmap in Figure 2), the pattern is similar that there are also two sets of classifications. The difference to the top heatmap is now the partitions where features are selected based on row variance (SD/CV/MAD) are more stable in the consensus partitioning procedure while partitions with features selected by ATC are less stable.

Comparing classifications from row-scaling and non-row-scaling, the classifications are similar for both cases. Basically we can make the conclusion that, when rows are scaled, methods with ATC give more stable partitions and when rows are not scaled, methods with SD/CV/MAD give more stable partitions.

Figure 2. Classifications from all methods. Column order of the two heatmaps are the same.

Figure 2. Classifications from all methods. Column order of the two heatmaps are the same.

To look closer on the different impact on consensus partitioning of applying row-scaling or not, we select the results by ATC:skmeans for the case when matrix rows are scaled and the results by MAD:kmeans for the case when matrix rows are not scaled. The partitionings are stable for the two methods in their settings. Figure 3 illustrates how the two classifications correspond.

Figure 3. Conseusus partitions from ATC:skmeans and MAD:kmeans methods.

Figure 3. Conseusus partitions from ATC:skmeans and MAD:kmeans methods.

We can confirm that MAD:kmeans, row unscaled classification fits very well to the AML/ALL classification, while a subset of ALL samples are classified as the same group as AML samples for the ATC:skmeans, row scaled classification (the green samples on the most right side).

To make it easier to describe, we term the classification from the scaled matrix as \(C_{s, 2}\) (or C_{s,2} if it cannot be rendered as math symbols) and the classification from the unscaled matrix as \(C_{u,2}\) (or C_{u,2}).

We can confirm the separation of the two groups by PCA visualization. PCA is applied to the scaled matrix in Figure 4A and to the unscaled matrix in Figure 4B. The two plots shows the two classifications can both separate samples very well and seem very reasonable.

Figure 4. PCA plots for visualizing the two-group classification. Classification on the left plot is from $C_{s,2}$ and on the right is from $C_{u,2}$.

Figure 4. PCA plots for visualizing the two-group classification. Classification on the left plot is from \(C_{s,2}\) and on the right is from \(C_{u,2}\).

Signature genes

Since there are two different classifications, we can next look at the signature genes that are significantly differentially expressed in the two groups, i.e. to compare the signature genes that support the two different classifications.

In Figure 5A and 5B, the significant genes are simply selected by t-test (FDR < 0.05). According to the heatmaps illustrated in Figure 5A and 5B, it seems the two different classification are all reasonable that there are many significant genes supporting them, although the number of significant genes in \(C_{s,2}\) are approximate 2 fold more than in \(C_{u,2}\).

Rows are scaled

Figure 5A. Signature genes from $C_{s,2}$.

Figure 5A. Signature genes from \(C_{s,2}\).

Rows are unscaled

Figure 5A. Signature genes from $C_{u,2}$.

Figure 5A. Signature genes from \(C_{u,2}\).

The two sets of signature genes have quite large overlap, and they also have their own unique set of genes. \(C_{s,2}\) has 1106 (61%) specific genes and \(C_{u,2}\) has 353 (33%) specific genes (Figure 6).

Figure 6. Overlap of signature genes in $C_{s,2}$ and $C_{u,2}$.

Figure 6. Overlap of signature genes in \(C_{s,2}\) and \(C_{u,2}\).

To see the difference of the three sets of signature genes in Figure 6, we make heatmaps for the signature genes specific in classification \(C_{s, 2}\), specific in \(C_{u, 2}\) and those common in the two classifications.

As illustrated in Figure 7A and 7C, the expression patterns for the signature genes specific in \(C_{s,2}\) or \(C_{u,2}\) are clean that the samples are not separable in the other classification, while in Figure 7B where the signature genes are shared by the two classifications, the signature genes show intermeidate expression patterns in the samples that disagree in the two classifcations, they can be classified to different groups by different methods.

Figure 7. Heatmaps of $C_{s,2}$ specific signatures, $C_{u,2}$ specific signatures and common signatures in the two classifcations.

Figure 7. Heatmaps of \(C_{s,2}\) specific signatures, \(C_{u,2}\) specific signatures and common signatures in the two classifcations.

We term the three categories of signature genes as group A/B/C and we apply Gene Ontology enrichment to the three set of genes by hypergenometric test (with the clusterProfiler package). We only use BP ontologies (Biological Process) and the significant GO terms are filtered by FDR < 0.01. The enriched GO terms are visualized as a heatmap in Figure 8 by their similarities between GO terms (with GOSemSim package). GO terms are split and clustered with the simplifyEnrichment package. The keywords of the summaries of GO functions in each cluster are visualized by word clouds.

Again, Figure 8 illustrates each set of genes have quite a lot enriched GO terms, which might imply both classification are biologically reasonable.

The complete list of the GO enrichment can be found at the end of this supplementary.

Figure 8. Gene ontology enrichment on the three sets of genes illustrated in Figure 7.

Figure 8. Gene ontology enrichment on the three sets of genes illustrated in Figure 7.

Conclusion

As a conclusion for the two-group classification analysis on Golub dataset, we can make following conclusions:

Gene Ontology enrichment

A (649 terms)

ID Description GeneRatio BgRatio pvalue p.adjust Count
GO:0009725 response to hormone 111/877 920/17913 0.0000 0.0000 111
GO:0051050 positive regulation of transport 111/877 942/17913 0.0000 0.0000 111
GO:0010243 response to organonitrogen compound 105/877 932/17913 0.0000 0.0000 105
GO:0071417 cellular response to organonitrogen compound 71/877 559/17913 0.0000 0.0000 71
GO:0033993 response to lipid 95/877 884/17913 0.0000 0.0000 95
GO:0007167 enzyme linked receptor protein signaling pathway 101/877 968/17913 0.0000 0.0000 101
GO:1901652 response to peptide 64/877 491/17913 0.0000 0.0000 64
GO:1901699 cellular response to nitrogen compound 74/877 620/17913 0.0000 0.0000 74
GO:0014070 response to organic cyclic compound 93/877 879/17913 0.0000 0.0000 93
GO:0023061 signal release 58/877 433/17913 0.0000 0.0000 58
GO:0070482 response to oxygen levels 54/877 389/17913 0.0000 0.0000 54
GO:0032870 cellular response to hormone stimulus 73/877 647/17913 0.0000 0.0000 73
GO:1903530 regulation of secretion by cell 77/877 703/17913 0.0000 0.0000 77
GO:0009611 response to wounding 74/877 665/17913 0.0000 0.0000 74
GO:0042493 response to drug 95/877 958/17913 0.0000 0.0000 95
GO:1901653 cellular response to peptide 50/877 364/17913 0.0000 0.0000 50
GO:0051046 regulation of secretion 80/877 757/17913 0.0000 0.0000 80
GO:0036293 response to decreased oxygen levels 49/877 365/17913 0.0000 0.0000 49
GO:0001666 response to hypoxia 48/877 354/17913 0.0000 0.0000 48
GO:0043434 response to peptide hormone 52/877 404/17913 0.0000 0.0000 52
GO:0046879 hormone secretion 43/877 301/17913 0.0000 0.0000 43
GO:0002790 peptide secretion 65/877 582/17913 0.0000 0.0000 65
GO:0090087 regulation of peptide transport 74/877 706/17913 0.0000 0.0000 74
GO:0051098 regulation of binding 48/877 368/17913 0.0000 0.0000 48
GO:0030072 peptide hormone secretion 37/877 241/17913 0.0000 0.0000 37
GO:0009914 hormone transport 43/877 311/17913 0.0000 0.0000 43
GO:0019725 cellular homeostasis 81/877 814/17913 0.0000 0.0000 81
GO:0042391 regulation of membrane potential 48/877 374/17913 0.0000 0.0000 48
GO:0043269 regulation of ion transport 68/877 639/17913 0.0000 0.0000 68
GO:0046883 regulation of hormone secretion 37/877 254/17913 0.0000 0.0000 37
GO:0043066 negative regulation of apoptotic process 85/877 894/17913 0.0000 0.0000 85
GO:0055082 cellular chemical homeostasis 69/877 666/17913 0.0000 0.0000 69
GO:0098657 import into cell 75/877 751/17913 0.0000 0.0000 75
GO:0061564 axon development 52/877 438/17913 0.0000 0.0000 52
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 69/877 669/17913 0.0000 0.0000 69
GO:0032880 regulation of protein localization 90/877 979/17913 0.0000 0.0000 90
GO:0007417 central nervous system development 87/877 935/17913 0.0000 0.0000 87
GO:0007409 axonogenesis 48/877 393/17913 0.0000 0.0000 48
GO:1903532 positive regulation of secretion by cell 47/877 381/17913 0.0000 0.0000 47
GO:0071375 cellular response to peptide hormone stimulus 40/877 297/17913 0.0000 0.0000 40
GO:0042327 positive regulation of phosphorylation 88/877 955/17913 0.0000 0.0000 88
GO:0048732 gland development 50/877 422/17913 0.0000 0.0000 50
GO:0060322 head development 73/877 738/17913 0.0000 0.0000 73
GO:0046887 positive regulation of hormone secretion 24/877 125/17913 0.0000 0.0000 24
GO:0043069 negative regulation of programmed cell death 85/877 916/17913 0.0000 0.0000 85
GO:0099536 synaptic signaling 63/877 601/17913 0.0000 0.0000 63
GO:0048534 hematopoietic or lymphoid organ development 83/877 890/17913 0.0000 0.0000 83
GO:0090276 regulation of peptide hormone secretion 31/877 199/17913 0.0000 0.0000 31
GO:0060341 regulation of cellular localization 81/877 863/17913 0.0000 0.0000 81
GO:0002520 immune system development 86/877 938/17913 0.0000 0.0000 86
GO:0007268 chemical synaptic transmission 62/877 591/17913 0.0000 0.0000 62
GO:0098916 anterograde trans-synaptic signaling 62/877 591/17913 0.0000 0.0000 62
GO:0048729 tissue morphogenesis 65/877 635/17913 0.0000 0.0000 65
GO:0050804 modulation of chemical synaptic transmission 47/877 393/17913 0.0000 0.0000 47
GO:0006936 muscle contraction 43/877 343/17913 0.0000 0.0000 43
GO:0009636 response to toxic substance 55/877 499/17913 0.0000 0.0000 55
GO:0099177 regulation of trans-synaptic signaling 47/877 394/17913 0.0000 0.0000 47
GO:0008285 negative regulation of cell proliferation 73/877 751/17913 0.0000 0.0000 73
GO:0070201 regulation of establishment of protein localization 71/877 723/17913 0.0000 0.0000 71
GO:0099537 trans-synaptic signaling 62/877 596/17913 0.0000 0.0000 62
GO:0048863 stem cell differentiation 34/877 237/17913 0.0000 0.0000 34
GO:0051047 positive regulation of secretion 48/877 409/17913 0.0000 0.0000 48
GO:0001505 regulation of neurotransmitter levels 41/877 321/17913 0.0000 0.0000 41
GO:0010817 regulation of hormone levels 55/877 503/17913 0.0000 0.0000 55
GO:0048511 rhythmic process 38/877 287/17913 0.0000 0.0000 38
GO:0030097 hemopoiesis 79/877 847/17913 0.0000 0.0000 79
GO:0032386 regulation of intracellular transport 47/877 400/17913 0.0000 0.0000 47
GO:0032868 response to insulin 35/877 252/17913 0.0000 0.0000 35
GO:0048545 response to steroid hormone 45/877 375/17913 0.0000 0.0000 45
GO:0099003 vesicle-mediated transport in synapse 28/877 174/17913 0.0000 0.0000 28
GO:0009306 protein secretion 58/877 549/17913 0.0000 0.0000 58
GO:0072358 cardiovascular system development 75/877 792/17913 0.0000 0.0000 75
GO:0044419 interspecies interaction between organisms 84/877 928/17913 0.0000 0.0000 84
GO:0006935 chemotaxis 58/877 551/17913 0.0000 0.0000 58
GO:0002791 regulation of peptide secretion 53/877 483/17913 0.0000 0.0000 53
GO:0034762 regulation of transmembrane transport 57/877 538/17913 0.0000 0.0000 57
GO:0042330 taxis 58/877 553/17913 0.0000 0.0000 58
GO:0001944 vasculature development 74/877 784/17913 0.0000 0.0000 74
GO:0035239 tube morphogenesis 82/877 905/17913 0.0000 0.0000 82
GO:0003012 muscle system process 50/877 448/17913 0.0000 0.0000 50
GO:0009743 response to carbohydrate 32/877 224/17913 0.0000 0.0000 32
GO:0072507 divalent inorganic cation homeostasis 47/877 412/17913 0.0000 0.0000 47
GO:0051223 regulation of protein transport 66/877 677/17913 0.0000 0.0000 66
GO:0008284 positive regulation of cell proliferation 83/877 931/17913 0.0000 0.0000 83
GO:0007420 brain development 67/877 694/17913 0.0000 0.0000 67
GO:0006836 neurotransmitter transport 33/877 241/17913 0.0000 0.0000 33
GO:0072503 cellular divalent inorganic cation homeostasis 45/877 392/17913 0.0000 0.0000 45
GO:0043270 positive regulation of ion transport 35/877 266/17913 0.0000 0.0000 35
GO:0009266 response to temperature stimulus 31/877 219/17913 0.0000 0.0000 31
GO:0001568 blood vessel development 70/877 751/17913 0.0000 0.0000 70
GO:0016579 protein deubiquitination 34/877 260/17913 0.0000 0.0000 34
GO:1904951 positive regulation of establishment of protein localization 48/877 440/17913 0.0000 0.0000 48
GO:0032101 regulation of response to external stimulus 78/877 873/17913 0.0000 0.0000 78
GO:0070646 protein modification by small protein removal 35/877 273/17913 0.0000 0.0000 35
GO:0030001 metal ion transport 73/877 800/17913 0.0000 0.0000 73
GO:0001934 positive regulation of protein phosphorylation 80/877 907/17913 0.0000 0.0000 80
GO:0045471 response to ethanol 22/877 127/17913 0.0000 0.0000 22
GO:0050878 regulation of body fluid levels 52/877 499/17913 0.0000 0.0000 52
GO:0048514 blood vessel morphogenesis 64/877 670/17913 0.0000 0.0000 64
GO:0033674 positive regulation of kinase activity 55/877 541/17913 0.0000 0.0000 55
GO:0010959 regulation of metal ion transport 42/877 365/17913 0.0000 0.0000 42
GO:0018209 peptidyl-serine modification 33/877 252/17913 0.0000 0.0000 33
GO:0046677 response to antibiotic 39/877 328/17913 0.0000 0.0000 39
GO:0044403 symbiont process 78/877 884/17913 0.0000 0.0000 78
GO:0050778 positive regulation of immune response 73/877 809/17913 0.0000 0.0000 73
GO:0009894 regulation of catabolic process 80/877 916/17913 0.0000 0.0000 80
GO:0003013 circulatory system process 54/877 532/17913 0.0000 0.0000 54
GO:0030003 cellular cation homeostasis 53/877 518/17913 0.0000 0.0000 53
GO:0071407 cellular response to organic cyclic compound 54/877 533/17913 0.0000 0.0000 54
GO:0001525 angiogenesis 57/877 576/17913 0.0000 0.0000 57
GO:0090277 positive regulation of peptide hormone secretion 18/877 91/17913 0.0000 0.0000 18
GO:2001233 regulation of apoptotic signaling pathway 44/877 397/17913 0.0000 0.0000 44
GO:0031329 regulation of cellular catabolic process 73/877 814/17913 0.0000 0.0000 73
GO:0097190 apoptotic signaling pathway 57/877 579/17913 0.0000 0.0000 57
GO:0006875 cellular metal ion homeostasis 49/877 467/17913 0.0000 0.0000 49
GO:0048608 reproductive structure development 46/877 426/17913 0.0000 0.0000 46
GO:0051347 positive regulation of transferase activity 59/877 609/17913 0.0000 0.0000 59
GO:0055074 calcium ion homeostasis 43/877 388/17913 0.0000 0.0000 43
GO:0061458 reproductive system development 46/877 429/17913 0.0000 0.0000 46
GO:0030073 insulin secretion 28/877 200/17913 0.0000 0.0000 28
GO:0034284 response to monosaccharide 28/877 200/17913 0.0000 0.0000 28
GO:0000165 MAPK cascade 77/877 882/17913 0.0000 0.0000 77
GO:0007507 heart development 55/877 556/17913 0.0000 0.0000 55
GO:0048667 cell morphogenesis involved in neuron differentiation 51/877 500/17913 0.0000 0.0000 51
GO:0071453 cellular response to oxygen levels 31/877 237/17913 0.0000 0.0000 31
GO:0031347 regulation of defense response 77/877 885/17913 0.0000 0.0000 77
GO:0071363 cellular response to growth factor stimulus 63/877 674/17913 0.0000 0.0000 63
GO:0009749 response to glucose 27/877 190/17913 0.0000 0.0000 27
GO:0023014 signal transduction by protein phosphorylation 77/877 886/17913 0.0000 0.0000 77
GO:1902803 regulation of synaptic vesicle transport 16/877 76/17913 0.0000 0.0000 16
GO:0002793 positive regulation of peptide secretion 34/877 275/17913 0.0000 0.0000 34
GO:0006873 cellular ion homeostasis 53/877 531/17913 0.0000 0.0000 53
GO:0000904 cell morphogenesis involved in differentiation 60/877 632/17913 0.0000 0.0000 60
GO:0002253 activation of immune response 61/877 647/17913 0.0000 0.0000 61
GO:0042593 glucose homeostasis 30/877 227/17913 0.0000 0.0000 30
GO:0071396 cellular response to lipid 56/877 576/17913 0.0000 0.0000 56
GO:0009755 hormone-mediated signaling pathway 29/877 216/17913 0.0000 0.0000 29
GO:0033500 carbohydrate homeostasis 30/877 228/17913 0.0000 0.0000 30
GO:0006942 regulation of striated muscle contraction 18/877 96/17913 0.0000 0.0000 18
GO:0043065 positive regulation of apoptotic process 61/877 652/17913 0.0000 0.0000 61
GO:0044057 regulation of system process 57/877 594/17913 0.0000 0.0000 57
GO:0031667 response to nutrient levels 48/877 466/17913 0.0000 0.0000 48
GO:1903522 regulation of blood circulation 35/877 292/17913 0.0000 0.0000 35
GO:0009887 animal organ morphogenesis 83/877 989/17913 0.0000 0.0000 83
GO:0008015 blood circulation 52/877 523/17913 0.0000 0.0000 52
GO:0009746 response to hexose 27/877 195/17913 0.0000 0.0000 27
GO:0018105 peptidyl-serine phosphorylation 30/877 231/17913 0.0000 0.0000 30
GO:0016032 viral process 72/877 822/17913 0.0000 0.0000 72
GO:0002009 morphogenesis of an epithelium 52/877 527/17913 0.0000 0.0000 52
GO:0032869 cellular response to insulin stimulus 27/877 197/17913 0.0000 0.0000 27
GO:0006874 cellular calcium ion homeostasis 41/877 375/17913 0.0000 0.0000 41
GO:0070848 response to growth factor 64/877 704/17913 0.0000 0.0000 64
GO:0001816 cytokine production 68/877 765/17913 0.0000 0.0001 68
GO:0043068 positive regulation of programmed cell death 61/877 660/17913 0.0000 0.0001 61
GO:0051222 positive regulation of protein transport 43/877 403/17913 0.0000 0.0001 43
GO:0071214 cellular response to abiotic stimulus 36/877 310/17913 0.0000 0.0001 36
GO:0104004 cellular response to environmental stimulus 36/877 310/17913 0.0000 0.0001 36
GO:0120039 plasma membrane bounded cell projection morphogenesis 55/877 573/17913 0.0000 0.0001 55
GO:0000902 cell morphogenesis 75/877 874/17913 0.0000 0.0001 75
GO:0055080 cation homeostasis 56/877 588/17913 0.0000 0.0001 56
GO:0048812 neuron projection morphogenesis 54/877 559/17913 0.0000 0.0001 54
GO:0006887 exocytosis 74/877 862/17913 0.0000 0.0001 74
GO:0048858 cell projection morphogenesis 55/877 577/17913 0.0000 0.0001 55
GO:0015672 monovalent inorganic cation transport 48/877 477/17913 0.0000 0.0001 48
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 25/877 178/17913 0.0000 0.0001 25
GO:0042060 wound healing 53/877 550/17913 0.0000 0.0001 53
GO:0060627 regulation of vesicle-mediated transport 48/877 480/17913 0.0000 0.0001 48
GO:0040007 growth 79/877 948/17913 0.0000 0.0001 79
GO:0001101 response to acid chemical 37/877 330/17913 0.0000 0.0001 37
GO:0070838 divalent metal ion transport 46/877 454/17913 0.0000 0.0001 46
GO:0045786 negative regulation of cell cycle 57/877 613/17913 0.0000 0.0001 57
GO:0007568 aging 36/877 318/17913 0.0000 0.0001 36
GO:0009991 response to extracellular stimulus 49/877 498/17913 0.0000 0.0001 49
GO:0009408 response to heat 23/877 158/17913 0.0000 0.0001 23
GO:0043393 regulation of protein binding 28/877 217/17913 0.0000 0.0001 28
GO:0098771 inorganic ion homeostasis 56/877 600/17913 0.0000 0.0001 56
GO:0022898 regulation of transmembrane transporter activity 30/877 242/17913 0.0000 0.0001 30
GO:0006941 striated muscle contraction 24/877 170/17913 0.0000 0.0001 24
GO:0048771 tissue remodeling 24/877 170/17913 0.0000 0.0001 24
GO:0048489 synaptic vesicle transport 20/877 126/17913 0.0000 0.0001 20
GO:0097480 establishment of synaptic vesicle localization 20/877 126/17913 0.0000 0.0001 20
GO:0072511 divalent inorganic cation transport 46/877 458/17913 0.0000 0.0001 46
GO:0097479 synaptic vesicle localization 21/877 137/17913 0.0000 0.0001 21
GO:0045860 positive regulation of protein kinase activity 49/877 501/17913 0.0000 0.0001 49
GO:0000375 RNA splicing, via transesterification reactions 38/877 348/17913 0.0000 0.0001 38
GO:2000736 regulation of stem cell differentiation 19/877 116/17913 0.0000 0.0001 19
GO:0055065 metal ion homeostasis 51/877 531/17913 0.0000 0.0001 51
GO:0031175 neuron projection development 74/877 879/17913 0.0000 0.0001 74
GO:0010942 positive regulation of cell death 63/877 710/17913 0.0000 0.0001 63
GO:0036294 cellular response to decreased oxygen levels 28/877 220/17913 0.0000 0.0001 28
GO:0003015 heart process 33/877 284/17913 0.0000 0.0001 33
GO:0009308 amine metabolic process 20/877 128/17913 0.0000 0.0001 20
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 23/877 162/17913 0.0000 0.0001 23
GO:0050801 ion homeostasis 60/877 669/17913 0.0000 0.0001 60
GO:1904062 regulation of cation transmembrane transport 35/877 312/17913 0.0000 0.0001 35
GO:0098655 cation transmembrane transport 64/877 730/17913 0.0000 0.0001 64
GO:0007411 axon guidance 27/877 210/17913 0.0000 0.0001 27
GO:0071456 cellular response to hypoxia 27/877 210/17913 0.0000 0.0001 27
GO:0032990 cell part morphogenesis 55/877 595/17913 0.0000 0.0001 55
GO:0030855 epithelial cell differentiation 65/877 746/17913 0.0000 0.0001 65
GO:0051588 regulation of neurotransmitter transport 20/877 129/17913 0.0000 0.0001 20
GO:0034764 positive regulation of transmembrane transport 26/877 199/17913 0.0000 0.0001 26
GO:0050670 regulation of lymphocyte proliferation 26/877 199/17913 0.0000 0.0001 26
GO:0008016 regulation of heart contraction 30/877 249/17913 0.0000 0.0001 30
GO:0019221 cytokine-mediated signaling pathway 66/877 764/17913 0.0000 0.0001 66
GO:0050851 antigen receptor-mediated signaling pathway 28/877 224/17913 0.0000 0.0001 28
GO:0006937 regulation of muscle contraction 23/877 164/17913 0.0000 0.0001 23
GO:0007159 leukocyte cell-cell adhesion 36/877 328/17913 0.0000 0.0001 36
GO:0097485 neuron projection guidance 27/877 212/17913 0.0000 0.0001 27
GO:0009612 response to mechanical stimulus 26/877 200/17913 0.0000 0.0001 26
GO:0032944 regulation of mononuclear cell proliferation 26/877 200/17913 0.0000 0.0001 26
GO:0034765 regulation of ion transmembrane transport 45/877 453/17913 0.0000 0.0001 45
GO:2000027 regulation of animal organ morphogenesis 30/877 250/17913 0.0000 0.0001 30
GO:0098810 neurotransmitter reuptake 8/877 22/17913 0.0000 0.0001 8
GO:0051101 regulation of DNA binding 19/877 120/17913 0.0000 0.0002 19
GO:0006897 endocytosis 60/877 675/17913 0.0000 0.0002 60
GO:2001020 regulation of response to DNA damage stimulus 26/877 201/17913 0.0000 0.0002 26
GO:0045087 innate immune response 74/877 893/17913 0.0000 0.0002 74
GO:0045055 regulated exocytosis 66/877 768/17913 0.0000 0.0002 66
GO:0098660 inorganic ion transmembrane transport 63/877 722/17913 0.0000 0.0002 63
GO:0006954 inflammatory response 67/877 784/17913 0.0000 0.0002 67
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 37/877 344/17913 0.0000 0.0002 37
GO:0000398 mRNA splicing, via spliceosome 37/877 344/17913 0.0000 0.0002 37
GO:0070663 regulation of leukocyte proliferation 27/877 214/17913 0.0000 0.0002 27
GO:0050708 regulation of protein secretion 45/877 456/17913 0.0000 0.0002 45
GO:0044106 cellular amine metabolic process 19/877 121/17913 0.0000 0.0002 19
GO:0060048 cardiac muscle contraction 20/877 132/17913 0.0000 0.0002 20
GO:0090066 regulation of anatomical structure size 44/877 442/17913 0.0000 0.0002 44
GO:0033238 regulation of cellular amine metabolic process 15/877 80/17913 0.0000 0.0002 15
GO:0051090 regulation of DNA-binding transcription factor activity 43/877 429/17913 0.0000 0.0002 43
GO:0003006 developmental process involved in reproduction 58/877 649/17913 0.0000 0.0002 58
GO:0006816 calcium ion transport 42/877 415/17913 0.0000 0.0002 42
GO:2000300 regulation of synaptic vesicle exocytosis 14/877 71/17913 0.0000 0.0002 14
GO:0045597 positive regulation of cell differentiation 78/877 962/17913 0.0000 0.0002 78
GO:0071496 cellular response to external stimulus 35/877 320/17913 0.0000 0.0002 35
GO:0055117 regulation of cardiac muscle contraction 15/877 81/17913 0.0000 0.0002 15
GO:0001656 metanephros development 16/877 91/17913 0.0000 0.0002 16
GO:0050806 positive regulation of synaptic transmission 21/877 145/17913 0.0000 0.0002 21
GO:0001817 regulation of cytokine production 61/877 698/17913 0.0000 0.0002 61
GO:0050796 regulation of insulin secretion 23/877 169/17913 0.0000 0.0002 23
GO:1905330 regulation of morphogenesis of an epithelium 24/877 181/17913 0.0000 0.0002 24
GO:0043549 regulation of kinase activity 68/877 808/17913 0.0000 0.0002 68
GO:0046651 lymphocyte proliferation 29/877 244/17913 0.0000 0.0002 29
GO:0051924 regulation of calcium ion transport 29/877 244/17913 0.0000 0.0002 29
GO:0070661 leukocyte proliferation 31/877 270/17913 0.0000 0.0002 31
GO:0032409 regulation of transporter activity 30/877 257/17913 0.0000 0.0002 30
GO:0031669 cellular response to nutrient levels 27/877 220/17913 0.0000 0.0002 27
GO:0032943 mononuclear cell proliferation 29/877 246/17913 0.0000 0.0003 29
GO:0016071 mRNA metabolic process 68/877 815/17913 0.0000 0.0003 68
GO:0043620 regulation of DNA-templated transcription in response to stress 18/877 115/17913 0.0000 0.0003 18
GO:0050900 leukocyte migration 45/877 467/17913 0.0000 0.0003 45
GO:0042129 regulation of T cell proliferation 21/877 149/17913 0.0000 0.0003 21
GO:1903706 regulation of hemopoiesis 45/877 468/17913 0.0000 0.0003 45
GO:0032989 cellular component morphogenesis 77/877 960/17913 0.0000 0.0003 77
GO:0006886 intracellular protein transport 69/877 833/17913 0.0000 0.0003 69
GO:0007221 positive regulation of transcription of Notch receptor target 7/877 18/17913 0.0000 0.0003 7
GO:2001234 negative regulation of apoptotic signaling pathway 27/877 223/17913 0.0000 0.0003 27
GO:0002764 immune response-regulating signaling pathway 54/877 603/17913 0.0000 0.0003 54
GO:0010469 regulation of signaling receptor activity 53/877 588/17913 0.0000 0.0003 53
GO:0060047 heart contraction 31/877 275/17913 0.0000 0.0003 31
GO:0051100 negative regulation of binding 22/877 162/17913 0.0000 0.0003 22
GO:0006913 nucleocytoplasmic transport 33/877 302/17913 0.0000 0.0003 33
GO:0071322 cellular response to carbohydrate stimulus 20/877 139/17913 0.0000 0.0003 20
GO:0098693 regulation of synaptic vesicle cycle 17/877 106/17913 0.0000 0.0003 17
GO:0090257 regulation of muscle system process 29/877 251/17913 0.0000 0.0003 29
GO:0017144 drug metabolic process 66/877 792/17913 0.0000 0.0003 66
GO:0048013 ephrin receptor signaling pathway 15/877 86/17913 0.0000 0.0004 15
GO:0051169 nuclear transport 33/877 305/17913 0.0000 0.0004 33
GO:0045785 positive regulation of cell adhesion 39/877 388/17913 0.0000 0.0004 39
GO:0048589 developmental growth 55/877 624/17913 0.0000 0.0004 55
GO:0042098 T cell proliferation 23/877 177/17913 0.0000 0.0004 23
GO:0046683 response to organophosphorus 19/877 130/17913 0.0000 0.0004 19
GO:0045859 regulation of protein kinase activity 62/877 733/17913 0.0000 0.0004 62
GO:0060284 regulation of cell development 72/877 893/17913 0.0000 0.0004 72
GO:0048872 homeostasis of number of cells 28/877 241/17913 0.0000 0.0004 28
GO:0002757 immune response-activating signal transduction 51/877 567/17913 0.0000 0.0004 51
GO:0098662 inorganic cation transmembrane transport 56/877 643/17913 0.0000 0.0004 56
GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 17/877 109/17913 0.0000 0.0004 17
GO:0030163 protein catabolic process 66/877 799/17913 0.0000 0.0004 66
GO:0009314 response to radiation 42/877 435/17913 0.0000 0.0004 42
GO:0007548 sex differentiation 30/877 269/17913 0.0000 0.0005 30
GO:0030258 lipid modification 24/877 192/17913 0.0000 0.0005 24
GO:0040017 positive regulation of locomotion 51/877 570/17913 0.0000 0.0005 51
GO:1903169 regulation of calcium ion transmembrane transport 20/877 144/17913 0.0000 0.0005 20
GO:2000147 positive regulation of cell motility 49/877 540/17913 0.0000 0.0005 49
GO:0051272 positive regulation of cellular component movement 50/877 555/17913 0.0000 0.0005 50
GO:0050852 T cell receptor signaling pathway 23/877 180/17913 0.0000 0.0005 23
GO:0006352 DNA-templated transcription, initiation 27/877 231/17913 0.0000 0.0005 27
GO:0034612 response to tumor necrosis factor 31/877 284/17913 0.0000 0.0005 31
GO:0043401 steroid hormone mediated signaling pathway 23/877 181/17913 0.0000 0.0005 23
GO:0051099 positive regulation of binding 23/877 181/17913 0.0000 0.0005 23
GO:0046822 regulation of nucleocytoplasmic transport 16/877 100/17913 0.0000 0.0005 16
GO:0018149 peptide cross-linking 9/877 34/17913 0.0000 0.0005 9
GO:0030522 intracellular receptor signaling pathway 30/877 272/17913 0.0000 0.0006 30
GO:0008380 RNA splicing 42/877 440/17913 0.0000 0.0006 42
GO:0071560 cellular response to transforming growth factor beta stimulus 27/877 233/17913 0.0000 0.0006 27
GO:0002026 regulation of the force of heart contraction 8/877 27/17913 0.0000 0.0006 8
GO:0072207 metanephric epithelium development 8/877 27/17913 0.0000 0.0006 8
GO:0070555 response to interleukin-1 23/877 183/17913 0.0000 0.0006 23
GO:0043433 negative regulation of DNA-binding transcription factor activity 22/877 171/17913 0.0000 0.0006 22
GO:1903311 regulation of mRNA metabolic process 30/877 275/17913 0.0000 0.0007 30
GO:0033555 multicellular organismal response to stress 13/877 71/17913 0.0000 0.0007 13
GO:0051952 regulation of amine transport 13/877 71/17913 0.0000 0.0007 13
GO:0045664 regulation of neuron differentiation 53/877 609/17913 0.0000 0.0007 53
GO:0051480 regulation of cytosolic calcium ion concentration 31/877 289/17913 0.0000 0.0007 31
GO:0032526 response to retinoic acid 16/877 103/17913 0.0000 0.0007 16
GO:0048857 neural nucleus development 12/877 62/17913 0.0000 0.0007 12
GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling 52/877 596/17913 0.0000 0.0007 52
GO:0019932 second-messenger-mediated signaling 36/877 360/17913 0.0000 0.0007 36
GO:1902036 regulation of hematopoietic stem cell differentiation 13/877 72/17913 0.0000 0.0008 13
GO:0030155 regulation of cell adhesion 56/877 659/17913 0.0000 0.0008 56
GO:0002696 positive regulation of leukocyte activation 32/877 305/17913 0.0000 0.0008 32
GO:0022409 positive regulation of cell-cell adhesion 28/877 251/17913 0.0000 0.0008 28
GO:0031668 cellular response to extracellular stimulus 28/877 251/17913 0.0000 0.0008 28
GO:0051591 response to cAMP 15/877 93/17913 0.0000 0.0008 15
GO:0030879 mammary gland development 19/877 138/17913 0.0000 0.0008 19
GO:0070252 actin-mediated cell contraction 17/877 115/17913 0.0000 0.0008 17
GO:0044706 multi-multicellular organism process 26/877 225/17913 0.0000 0.0008 26
GO:0099504 synaptic vesicle cycle 21/877 162/17913 0.0000 0.0008 21
GO:0017157 regulation of exocytosis 23/877 187/17913 0.0000 0.0008 23
GO:0002768 immune response-regulating cell surface receptor signaling pathway 41/877 434/17913 0.0000 0.0008 41
GO:0046649 lymphocyte activation 54/877 630/17913 0.0000 0.0008 54
GO:0060218 hematopoietic stem cell differentiation 14/877 83/17913 0.0000 0.0008 14
GO:0060078 regulation of postsynaptic membrane potential 18/877 127/17913 0.0000 0.0008 18
GO:0071559 response to transforming growth factor beta 27/877 239/17913 0.0000 0.0008 27
GO:0050727 regulation of inflammatory response 44/877 479/17913 0.0000 0.0008 44
GO:0071356 cellular response to tumor necrosis factor 29/877 266/17913 0.0000 0.0008 29
GO:2001236 regulation of extrinsic apoptotic signaling pathway 20/877 151/17913 0.0000 0.0008 20
GO:1903039 positive regulation of leukocyte cell-cell adhesion 25/877 214/17913 0.0001 0.0009 25
GO:0051168 nuclear export 22/877 176/17913 0.0001 0.0009 22
GO:0007599 hemostasis 34/877 336/17913 0.0001 0.0009 34
GO:0051338 regulation of transferase activity 71/877 903/17913 0.0001 0.0009 71
GO:0051707 response to other organism 71/877 903/17913 0.0001 0.0009 71
GO:1901019 regulation of calcium ion transmembrane transporter activity 14/877 84/17913 0.0001 0.0009 14
GO:1903037 regulation of leukocyte cell-cell adhesion 31/877 295/17913 0.0001 0.0009 31
GO:0043207 response to external biotic stimulus 71/877 905/17913 0.0001 0.0009 71
GO:0051590 positive regulation of neurotransmitter transport 9/877 37/17913 0.0001 0.0009 9
GO:0080135 regulation of cellular response to stress 59/877 713/17913 0.0001 0.0009 59
GO:0010720 positive regulation of cell development 47/877 528/17913 0.0001 0.0010 47
GO:0072593 reactive oxygen species metabolic process 29/877 269/17913 0.0001 0.0010 29
GO:0032388 positive regulation of intracellular transport 24/877 203/17913 0.0001 0.0010 24
GO:0045766 positive regulation of angiogenesis 24/877 203/17913 0.0001 0.0010 24
GO:0006397 mRNA processing 45/877 499/17913 0.0001 0.0010 45
GO:0043410 positive regulation of MAPK cascade 45/877 499/17913 0.0001 0.0010 45
GO:0010332 response to gamma radiation 11/877 55/17913 0.0001 0.0010 11
GO:0006367 transcription initiation from RNA polymerase II promoter 22/877 178/17913 0.0001 0.0010 22
GO:0040008 regulation of growth 56/877 668/17913 0.0001 0.0010 56
GO:1901532 regulation of hematopoietic progenitor cell differentiation 14/877 85/17913 0.0001 0.0010 14
GO:0033002 muscle cell proliferation 27/877 243/17913 0.0001 0.0010 27
GO:0046928 regulation of neurotransmitter secretion 15/877 96/17913 0.0001 0.0010 15
GO:0008361 regulation of cell size 20/877 154/17913 0.0001 0.0010 20
GO:0071300 cellular response to retinoic acid 12/877 65/17913 0.0001 0.0010 12
GO:0001678 cellular glucose homeostasis 19/877 142/17913 0.0001 0.0010 19
GO:1901796 regulation of signal transduction by p53 class mediator 22/877 179/17913 0.0001 0.0011 22
GO:0045926 negative regulation of growth 27/877 244/17913 0.0001 0.0011 27
GO:0051051 negative regulation of transport 45/877 502/17913 0.0001 0.0011 45
GO:0051251 positive regulation of lymphocyte activation 28/877 258/17913 0.0001 0.0011 28
GO:0071326 cellular response to monosaccharide stimulus 18/877 131/17913 0.0001 0.0011 18
GO:0031960 response to corticosteroid 20/877 155/17913 0.0001 0.0011 20
GO:0002429 immune response-activating cell surface receptor signaling pathway 38/877 399/17913 0.0001 0.0011 38
GO:0097305 response to alcohol 26/877 232/17913 0.0001 0.0012 26
GO:0007565 female pregnancy 23/877 193/17913 0.0001 0.0012 23
GO:0015837 amine transport 13/877 76/17913 0.0001 0.0012 13
GO:0050767 regulation of neurogenesis 62/877 768/17913 0.0001 0.0012 62
GO:0051129 negative regulation of cellular component organization 56/877 673/17913 0.0001 0.0012 56
GO:0071347 cellular response to interleukin-1 20/877 156/17913 0.0001 0.0012 20
GO:0051249 regulation of lymphocyte activation 38/877 401/17913 0.0001 0.0012 38
GO:0072215 regulation of metanephros development 7/877 23/17913 0.0001 0.0013 7
GO:0072243 metanephric nephron epithelium development 7/877 23/17913 0.0001 0.0013 7
GO:0001819 positive regulation of cytokine production 41/877 446/17913 0.0001 0.0013 41
GO:0032412 regulation of ion transmembrane transporter activity 26/877 234/17913 0.0001 0.0013 26
GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 11/877 57/17913 0.0001 0.0013 11
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 13/877 77/17913 0.0001 0.0013 13
GO:0014074 response to purine-containing compound 19/877 145/17913 0.0001 0.0013 19
GO:0035567 non-canonical Wnt signaling pathway 19/877 145/17913 0.0001 0.0013 19
GO:0001503 ossification 37/877 388/17913 0.0001 0.0013 37
GO:0001504 neurotransmitter uptake 9/877 39/17913 0.0001 0.0013 9
GO:0007596 blood coagulation 33/877 331/17913 0.0001 0.0013 33
GO:0009790 embryo development 74/877 968/17913 0.0001 0.0013 74
GO:0031103 axon regeneration 10/877 48/17913 0.0001 0.0014 10
GO:0022407 regulation of cell-cell adhesion 37/877 389/17913 0.0001 0.0014 37
GO:0030100 regulation of endocytosis 28/877 262/17913 0.0001 0.0014 28
GO:0043488 regulation of mRNA stability 20/877 158/17913 0.0001 0.0014 20
GO:0050867 positive regulation of cell activation 32/877 319/17913 0.0001 0.0015 32
GO:0046007 negative regulation of activated T cell proliferation 5/877 11/17913 0.0001 0.0015 5
GO:0050805 negative regulation of synaptic transmission 12/877 68/17913 0.0001 0.0015 12
GO:0016079 synaptic vesicle exocytosis 15/877 100/17913 0.0001 0.0015 15
GO:0001508 action potential 17/877 123/17913 0.0001 0.0015 17
GO:0015980 energy derivation by oxidation of organic compounds 28/877 264/17913 0.0001 0.0015 28
GO:0048660 regulation of smooth muscle cell proliferation 21/877 172/17913 0.0001 0.0015 21
GO:0050870 positive regulation of T cell activation 23/877 198/17913 0.0001 0.0016 23
GO:1902600 proton transmembrane transport 19/877 148/17913 0.0001 0.0017 19
GO:1903305 regulation of regulated secretory pathway 18/877 136/17913 0.0001 0.0017 18
GO:0071295 cellular response to vitamin 8/877 32/17913 0.0001 0.0017 8
GO:0050817 coagulation 33/877 337/17913 0.0001 0.0018 33
GO:0007269 neurotransmitter secretion 19/877 149/17913 0.0001 0.0018 19
GO:0048659 smooth muscle cell proliferation 21/877 174/17913 0.0001 0.0018 21
GO:0050673 epithelial cell proliferation 39/877 425/17913 0.0001 0.0018 39
GO:1901342 regulation of vasculature development 39/877 425/17913 0.0001 0.0018 39
GO:0017158 regulation of calcium ion-dependent exocytosis 14/877 91/17913 0.0001 0.0019 14
GO:0030335 positive regulation of cell migration 45/877 516/17913 0.0001 0.0019 45
GO:0099643 signal release from synapse 19/877 150/17913 0.0001 0.0019 19
GO:0007623 circadian rhythm 23/877 201/17913 0.0001 0.0019 23
GO:0002260 lymphocyte homeostasis 11/877 60/17913 0.0001 0.0019 11
GO:0006091 generation of precursor metabolites and energy 44/877 502/17913 0.0001 0.0020 44
GO:0045765 regulation of angiogenesis 36/877 383/17913 0.0001 0.0020 36
GO:0006611 protein export from nucleus 20/877 163/17913 0.0001 0.0020 20
GO:0043487 regulation of RNA stability 20/877 163/17913 0.0001 0.0020 20
GO:0099565 chemical synaptic transmission, postsynaptic 15/877 103/17913 0.0001 0.0020 15
GO:0015696 ammonium transport 13/877 81/17913 0.0001 0.0020 13
GO:0007584 response to nutrient 24/877 215/17913 0.0001 0.0020 24
GO:0060249 anatomical structure homeostasis 38/877 413/17913 0.0001 0.0020 38
GO:0019884 antigen processing and presentation of exogenous antigen 21/877 176/17913 0.0001 0.0020 21
GO:0050678 regulation of epithelial cell proliferation 35/877 369/17913 0.0001 0.0020 35
GO:0042110 T cell activation 40/877 443/17913 0.0001 0.0020 40
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 8/877 33/17913 0.0001 0.0020 8
GO:0051954 positive regulation of amine transport 8/877 33/17913 0.0001 0.0020 8
GO:0050714 positive regulation of protein secretion 27/877 256/17913 0.0002 0.0021 27
GO:0097094 craniofacial suture morphogenesis 6/877 18/17913 0.0002 0.0021 6
GO:0051384 response to glucocorticoid 18/877 139/17913 0.0002 0.0021 18
GO:0017156 calcium ion regulated exocytosis 17/877 127/17913 0.0002 0.0021 17
GO:0051960 regulation of nervous system development 67/877 870/17913 0.0002 0.0021 67
GO:0071383 cellular response to steroid hormone stimulus 26/877 243/17913 0.0002 0.0021 26
GO:0006521 regulation of cellular amino acid metabolic process 11/877 61/17913 0.0002 0.0022 11
GO:0019395 fatty acid oxidation 14/877 93/17913 0.0002 0.0022 14
GO:0009607 response to biotic stimulus 71/877 938/17913 0.0002 0.0022 71
GO:0032355 response to estradiol 17/877 128/17913 0.0002 0.0023 17
GO:0071333 cellular response to glucose stimulus 17/877 128/17913 0.0002 0.0023 17
GO:0060485 mesenchyme development 27/877 258/17913 0.0002 0.0023 27
GO:0044257 cellular protein catabolic process 53/877 648/17913 0.0002 0.0024 53
GO:0034605 cellular response to heat 16/877 117/17913 0.0002 0.0024 16
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 14/877 94/17913 0.0002 0.0024 14
GO:0035265 organ growth 21/877 179/17913 0.0002 0.0024 21
GO:1901385 regulation of voltage-gated calcium channel activity 8/877 34/17913 0.0002 0.0024 8
GO:1904018 positive regulation of vasculature development 25/877 232/17913 0.0002 0.0024 25
GO:1903827 regulation of cellular protein localization 44/877 509/17913 0.0002 0.0025 44
GO:0030162 regulation of proteolysis 60/877 762/17913 0.0002 0.0025 60
GO:0071377 cellular response to glucagon stimulus 7/877 26/17913 0.0002 0.0025 7
GO:0072202 cell differentiation involved in metanephros development 7/877 26/17913 0.0002 0.0025 7
GO:0033209 tumor necrosis factor-mediated signaling pathway 20/877 167/17913 0.0002 0.0026 20
GO:0071331 cellular response to hexose stimulus 17/877 130/17913 0.0002 0.0026 17
GO:0007589 body fluid secretion 14/877 95/17913 0.0002 0.0027 14
GO:0034440 lipid oxidation 14/877 95/17913 0.0002 0.0027 14
GO:0060079 excitatory postsynaptic potential 14/877 95/17913 0.0002 0.0027 14
GO:2000696 regulation of epithelial cell differentiation involved in kidney development 6/877 19/17913 0.0002 0.0027 6
GO:1903829 positive regulation of cellular protein localization 31/877 318/17913 0.0002 0.0027 31
GO:0070997 neuron death 33/877 347/17913 0.0002 0.0027 33
GO:0031099 regeneration 22/877 194/17913 0.0002 0.0028 22
GO:1905475 regulation of protein localization to membrane 21/877 181/17913 0.0002 0.0028 21
GO:0019933 cAMP-mediated signaling 18/877 143/17913 0.0002 0.0028 18
GO:0010035 response to inorganic substance 45/877 528/17913 0.0002 0.0028 45
GO:0048738 cardiac muscle tissue development 24/877 221/17913 0.0002 0.0028 24
GO:0001906 cell killing 19/877 156/17913 0.0002 0.0029 19
GO:0048167 regulation of synaptic plasticity 20/877 169/17913 0.0002 0.0029 20
GO:0035850 epithelial cell differentiation involved in kidney development 9/877 44/17913 0.0002 0.0029 9
GO:0030048 actin filament-based movement 17/877 132/17913 0.0002 0.0031 17
GO:0060401 cytosolic calcium ion transport 19/877 157/17913 0.0002 0.0031 19
GO:0062012 regulation of small molecule metabolic process 39/877 439/17913 0.0002 0.0031 39
GO:0043254 regulation of protein complex assembly 37/877 409/17913 0.0002 0.0031 37
GO:0043408 regulation of MAPK cascade 55/877 689/17913 0.0002 0.0031 55
GO:0007610 behavior 48/877 578/17913 0.0003 0.0031 48
GO:0097529 myeloid leukocyte migration 20/877 170/17913 0.0003 0.0031 20
GO:0061005 cell differentiation involved in kidney development 10/877 54/17913 0.0003 0.0031 10
GO:0050863 regulation of T cell activation 30/877 307/17913 0.0003 0.0031 30
GO:0060123 regulation of growth hormone secretion 5/877 13/17913 0.0003 0.0031 5
GO:0060452 positive regulation of cardiac muscle contraction 5/877 13/17913 0.0003 0.0031 5
GO:0072182 regulation of nephron tubule epithelial cell differentiation 5/877 13/17913 0.0003 0.0031 5
GO:1900272 negative regulation of long-term synaptic potentiation 5/877 13/17913 0.0003 0.0031 5
GO:0050769 positive regulation of neurogenesis 40/877 455/17913 0.0003 0.0031 40
GO:0031348 negative regulation of defense response 25/877 237/17913 0.0003 0.0032 25
GO:0060402 calcium ion transport into cytosol 18/877 145/17913 0.0003 0.0032 18
GO:0046777 protein autophosphorylation 23/877 210/17913 0.0003 0.0032 23
GO:0002444 myeloid leukocyte mediated immunity 46/877 549/17913 0.0003 0.0033 46
GO:0048598 embryonic morphogenesis 47/877 565/17913 0.0003 0.0034 47
GO:0033762 response to glucagon 8/877 36/17913 0.0003 0.0034 8
GO:0046825 regulation of protein export from nucleus 8/877 36/17913 0.0003 0.0034 8
GO:0014823 response to activity 11/877 65/17913 0.0003 0.0034 11
GO:0002027 regulation of heart rate 14/877 98/17913 0.0003 0.0035 14
GO:0050865 regulation of cell activation 45/877 535/17913 0.0003 0.0035 45
GO:0010975 regulation of neuron projection development 40/877 458/17913 0.0003 0.0035 40
GO:0031102 neuron projection regeneration 10/877 55/17913 0.0003 0.0035 10
GO:0032615 interleukin-12 production 10/877 55/17913 0.0003 0.0035 10
GO:0098586 cellular response to virus 10/877 55/17913 0.0003 0.0035 10
GO:0051650 establishment of vesicle localization 26/877 253/17913 0.0003 0.0035 26
GO:0035270 endocrine system development 16/877 122/17913 0.0003 0.0035 16
GO:0048638 regulation of developmental growth 31/877 325/17913 0.0003 0.0037 31
GO:0003180 aortic valve morphogenesis 7/877 28/17913 0.0003 0.0037 7
GO:0060292 long-term synaptic depression 7/877 28/17913 0.0003 0.0037 7
GO:0045666 positive regulation of neuron differentiation 33/877 355/17913 0.0003 0.0038 33
GO:0006635 fatty acid beta-oxidation 11/877 66/17913 0.0003 0.0038 11
GO:0015844 monoamine transport 11/877 66/17913 0.0003 0.0038 11
GO:0001736 establishment of planar polarity 16/877 123/17913 0.0003 0.0038 16
GO:0007164 establishment of tissue polarity 16/877 123/17913 0.0003 0.0038 16
GO:0002694 regulation of leukocyte activation 42/877 492/17913 0.0003 0.0039 42
GO:0003018 vascular process in circulatory system 19/877 161/17913 0.0003 0.0040 19
GO:0002478 antigen processing and presentation of exogenous peptide antigen 20/877 174/17913 0.0003 0.0040 20
GO:0001755 neural crest cell migration 8/877 37/17913 0.0003 0.0040 8
GO:0051648 vesicle localization 27/877 270/17913 0.0004 0.0041 27
GO:1901214 regulation of neuron death 30/877 313/17913 0.0004 0.0041 30
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 14/877 100/17913 0.0004 0.0041 14
GO:0043062 extracellular structure organization 35/877 387/17913 0.0004 0.0042 35
GO:0048002 antigen processing and presentation of peptide antigen 21/877 188/17913 0.0004 0.0042 21
GO:0070268 cornification 15/877 112/17913 0.0004 0.0042 15
GO:0010506 regulation of autophagy 30/877 314/17913 0.0004 0.0043 30
GO:0007517 muscle organ development 36/877 403/17913 0.0004 0.0043 36
GO:0016042 lipid catabolic process 29/877 300/17913 0.0004 0.0044 29
GO:0002275 myeloid cell activation involved in immune response 45/877 542/17913 0.0004 0.0044 45
GO:0048588 developmental cell growth 23/877 216/17913 0.0004 0.0044 23
GO:0050671 positive regulation of lymphocyte proliferation 16/877 125/17913 0.0004 0.0045 16
GO:0048675 axon extension 14/877 101/17913 0.0004 0.0045 14
GO:0032535 regulation of cellular component size 30/877 315/17913 0.0004 0.0045 30
GO:0045333 cellular respiration 20/877 176/17913 0.0004 0.0045 20
GO:0016572 histone phosphorylation 8/877 38/17913 0.0004 0.0047 8
GO:0030901 midbrain development 13/877 90/17913 0.0004 0.0047 13
GO:0002683 negative regulation of immune system process 39/877 451/17913 0.0004 0.0047 39
GO:0009161 ribonucleoside monophosphate metabolic process 31/877 331/17913 0.0004 0.0047 31
GO:0030856 regulation of epithelial cell differentiation 18/877 151/17913 0.0004 0.0048 18
GO:0032024 positive regulation of insulin secretion 11/877 68/17913 0.0004 0.0048 11
GO:1903524 positive regulation of blood circulation 11/877 68/17913 0.0004 0.0048 11
GO:0032946 positive regulation of mononuclear cell proliferation 16/877 126/17913 0.0004 0.0048 16
GO:0097006 regulation of plasma lipoprotein particle levels 14/877 102/17913 0.0004 0.0048 14
GO:0009167 purine ribonucleoside monophosphate metabolic process 30/877 317/17913 0.0004 0.0048 30
GO:0032147 activation of protein kinase activity 29/877 303/17913 0.0005 0.0050 29
GO:0007369 gastrulation 20/877 178/17913 0.0005 0.0050 20
GO:0061013 regulation of mRNA catabolic process 20/877 178/17913 0.0005 0.0050 20
GO:0061138 morphogenesis of a branching epithelium 20/877 178/17913 0.0005 0.0050 20
GO:0034767 positive regulation of ion transmembrane transport 18/877 152/17913 0.0005 0.0051 18
GO:0009126 purine nucleoside monophosphate metabolic process 30/877 318/17913 0.0005 0.0051 30
GO:0043299 leukocyte degranulation 44/877 532/17913 0.0005 0.0053 44
GO:2001023 regulation of response to drug 12/877 80/17913 0.0005 0.0053 12
GO:0072073 kidney epithelium development 17/877 140/17913 0.0005 0.0053 17
GO:1904064 positive regulation of cation transmembrane transport 17/877 140/17913 0.0005 0.0053 17
GO:1902991 regulation of amyloid precursor protein catabolic process 7/877 30/17913 0.0005 0.0053 7
GO:0006974 cellular response to DNA damage stimulus 60/877 791/17913 0.0005 0.0054 60
GO:0019935 cyclic-nucleotide-mediated signaling 19/877 166/17913 0.0005 0.0054 19
GO:0045823 positive regulation of heart contraction 8/877 39/17913 0.0005 0.0054 8
GO:0019882 antigen processing and presentation 23/877 220/17913 0.0005 0.0054 23
GO:0033157 regulation of intracellular protein transport 23/877 220/17913 0.0005 0.0054 23
GO:0035637 multicellular organismal signaling 21/877 193/17913 0.0005 0.0055 21
GO:0010038 response to metal ion 31/877 335/17913 0.0005 0.0056 31
GO:2001022 positive regulation of response to DNA damage stimulus 13/877 92/17913 0.0005 0.0056 13
GO:0031214 biomineral tissue development 18/877 154/17913 0.0005 0.0058 18
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 5/877 15/17913 0.0006 0.0058 5
GO:0072160 nephron tubule epithelial cell differentiation 5/877 15/17913 0.0006 0.0058 5
GO:0061061 muscle structure development 51/877 647/17913 0.0006 0.0058 51
GO:0009416 response to light stimulus 29/877 307/17913 0.0006 0.0059 29
GO:0030518 intracellular steroid hormone receptor signaling pathway 16/877 129/17913 0.0006 0.0059 16
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 30/877 323/17913 0.0006 0.0063 30
GO:0009615 response to virus 30/877 323/17913 0.0006 0.0063 30
GO:0042987 amyloid precursor protein catabolic process 8/877 40/17913 0.0006 0.0063 8
GO:0050832 defense response to fungus 8/877 40/17913 0.0006 0.0063 8
GO:0046824 positive regulation of nucleocytoplasmic transport 10/877 60/17913 0.0006 0.0063 10
GO:0002443 leukocyte mediated immunity 61/877 814/17913 0.0006 0.0063 61
GO:0099084 postsynaptic specialization organization 7/877 31/17913 0.0006 0.0063 7
GO:1903708 positive regulation of hemopoiesis 20/877 182/17913 0.0006 0.0063 20
GO:0031670 cellular response to nutrient 11/877 71/17913 0.0006 0.0065 11
GO:0050771 negative regulation of axonogenesis 9/877 50/17913 0.0006 0.0065 9
GO:0051966 regulation of synaptic transmission, glutamatergic 9/877 50/17913 0.0006 0.0065 9
GO:0048640 negative regulation of developmental growth 13/877 94/17913 0.0006 0.0066 13
GO:0043200 response to amino acid 14/877 106/17913 0.0007 0.0067 14
GO:0055017 cardiac muscle tissue growth 14/877 106/17913 0.0007 0.0067 14
GO:0045165 cell fate commitment 24/877 238/17913 0.0007 0.0067 24
GO:0072170 metanephric tubule development 6/877 23/17913 0.0007 0.0068 6
GO:2000637 positive regulation of gene silencing by miRNA 6/877 23/17913 0.0007 0.0068 6
GO:0006119 oxidative phosphorylation 16/877 131/17913 0.0007 0.0068 16
GO:0050728 negative regulation of inflammatory response 19/877 170/17913 0.0007 0.0068 19
GO:0010212 response to ionizing radiation 17/877 144/17913 0.0007 0.0069 17
GO:0034622 cellular protein-containing complex assembly 69/877 952/17913 0.0007 0.0069 69
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 12/877 83/17913 0.0007 0.0069 12
GO:0051928 positive regulation of calcium ion transport 15/877 119/17913 0.0007 0.0070 15
GO:0007179 transforming growth factor beta receptor signaling pathway 20/877 184/17913 0.0007 0.0071 20
GO:0060071 Wnt signaling pathway, planar cell polarity pathway 14/877 107/17913 0.0007 0.0072 14
GO:0009620 response to fungus 9/877 51/17913 0.0007 0.0074 9
GO:2000677 regulation of transcription regulatory region DNA binding 9/877 51/17913 0.0007 0.0074 9
GO:0010001 glial cell differentiation 22/877 212/17913 0.0007 0.0074 22
GO:0002244 hematopoietic progenitor cell differentiation 18/877 158/17913 0.0007 0.0074 18
GO:0002262 myeloid cell homeostasis 17/877 145/17913 0.0007 0.0074 17
GO:0003176 aortic valve development 7/877 32/17913 0.0008 0.0074 7
GO:0007190 activation of adenylate cyclase activity 7/877 32/17913 0.0008 0.0074 7
GO:0033028 myeloid cell apoptotic process 7/877 32/17913 0.0008 0.0074 7
GO:0046688 response to copper ion 7/877 32/17913 0.0008 0.0074 7
GO:0060562 epithelial tube morphogenesis 29/877 313/17913 0.0008 0.0075 29
GO:0006163 purine nucleotide metabolic process 43/877 528/17913 0.0008 0.0075 43
GO:0001776 leukocyte homeostasis 12/877 84/17913 0.0008 0.0075 12
GO:0090559 regulation of membrane permeability 12/877 84/17913 0.0008 0.0075 12
GO:0030252 growth hormone secretion 5/877 16/17913 0.0008 0.0075 5
GO:0045989 positive regulation of striated muscle contraction 5/877 16/17913 0.0008 0.0075 5
GO:0071871 response to epinephrine 5/877 16/17913 0.0008 0.0075 5
GO:0007204 positive regulation of cytosolic calcium ion concentration 25/877 255/17913 0.0008 0.0075 25
GO:0072521 purine-containing compound metabolic process 45/877 560/17913 0.0008 0.0075 45
GO:0002064 epithelial cell development 21/877 199/17913 0.0008 0.0075 21
GO:0048762 mesenchymal cell differentiation 21/877 199/17913 0.0008 0.0075 21
GO:0032102 negative regulation of response to external stimulus 31/877 343/17913 0.0008 0.0075 31
GO:0038093 Fc receptor signaling pathway 24/877 241/17913 0.0008 0.0076 24
GO:0097191 extrinsic apoptotic signaling pathway 22/877 213/17913 0.0008 0.0076 22
GO:0050880 regulation of blood vessel size 16/877 133/17913 0.0008 0.0076 16
GO:0016049 cell growth 39/877 466/17913 0.0008 0.0077 39
GO:0003208 cardiac ventricle morphogenesis 11/877 73/17913 0.0008 0.0077 11
GO:0002685 regulation of leukocyte migration 20/877 186/17913 0.0008 0.0077 20
GO:0010948 negative regulation of cell cycle process 31/877 344/17913 0.0008 0.0078 31
GO:0002687 positive regulation of leukocyte migration 15/877 121/17913 0.0008 0.0080 15
GO:0045596 negative regulation of cell differentiation 55/877 725/17913 0.0008 0.0081 55
GO:0060148 positive regulation of posttranscriptional gene silencing 6/877 24/17913 0.0009 0.0081 6
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 12/877 85/17913 0.0009 0.0081 12
GO:0035150 regulation of tube size 16/877 134/17913 0.0009 0.0081 16
GO:0070665 positive regulation of leukocyte proliferation 16/877 134/17913 0.0009 0.0081 16
GO:0019693 ribose phosphate metabolic process 43/877 531/17913 0.0009 0.0081 43
GO:0090175 regulation of establishment of planar polarity 14/877 109/17913 0.0009 0.0081 14
GO:0001909 leukocyte mediated cytotoxicity 13/877 97/17913 0.0009 0.0082 13
GO:1902750 negative regulation of cell cycle G2/M phase transition 13/877 97/17913 0.0009 0.0082 13
GO:0009150 purine ribonucleotide metabolic process 41/877 500/17913 0.0009 0.0083 41
GO:0042594 response to starvation 19/877 174/17913 0.0009 0.0084 19
GO:0007006 mitochondrial membrane organization 15/877 122/17913 0.0009 0.0085 15
GO:0060537 muscle tissue development 34/877 392/17913 0.0009 0.0086 34
GO:0050770 regulation of axonogenesis 17/877 148/17913 0.0009 0.0087 17
GO:0035690 cellular response to drug 32/877 362/17913 0.0009 0.0087 32
GO:0030432 peristalsis 4/877 10/17913 0.0009 0.0087 4
GO:0071639 positive regulation of monocyte chemotactic protein-1 production 4/877 10/17913 0.0009 0.0087 4
GO:0032602 chemokine production 12/877 86/17913 0.0010 0.0088 12
GO:0009895 negative regulation of catabolic process 27/877 288/17913 0.0010 0.0089 27
GO:0010522 regulation of calcium ion transport into cytosol 13/877 98/17913 0.0010 0.0089 13
GO:0006914 autophagy 39/877 471/17913 0.0010 0.0090 39
GO:0061919 process utilizing autophagic mechanism 39/877 471/17913 0.0010 0.0090 39
GO:0032655 regulation of interleukin-12 production 9/877 53/17913 0.0010 0.0090 9
GO:0042130 negative regulation of T cell proliferation 9/877 53/17913 0.0010 0.0090 9
GO:0044242 cellular lipid catabolic process 20/877 189/17913 0.0010 0.0091 20
GO:0032479 regulation of type I interferon production 15/877 123/17913 0.0010 0.0091 15
GO:0021762 substantia nigra development 8/877 43/17913 0.0010 0.0091 8
GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 8/877 43/17913 0.0010 0.0091 8
GO:1904646 cellular response to amyloid-beta 8/877 43/17913 0.0010 0.0091 8
GO:0035264 multicellular organism growth 17/877 149/17913 0.0010 0.0092 17
GO:0010769 regulation of cell morphogenesis involved in differentiation 25/877 260/17913 0.0010 0.0093 25
GO:0002283 neutrophil activation involved in immune response 40/877 488/17913 0.0010 0.0093 40
GO:1905710 positive regulation of membrane permeability 10/877 64/17913 0.0010 0.0093 10
GO:0009123 nucleoside monophosphate metabolic process 31/877 349/17913 0.0010 0.0093 31
GO:0090185 negative regulation of kidney development 5/877 17/17913 0.0011 0.0094 5
GO:0030099 myeloid cell differentiation 35/877 411/17913 0.0011 0.0096 35
GO:0001963 synaptic transmission, dopaminergic 6/877 25/17913 0.0011 0.0096 6
GO:0097435 supramolecular fiber organization 44/877 553/17913 0.0011 0.0096 44
GO:0090316 positive regulation of intracellular protein transport 17/877 150/17913 0.0011 0.0097 17
GO:0032735 positive regulation of interleukin-12 production 7/877 34/17913 0.0011 0.0099 7
GO:0060428 lung epithelium development 7/877 34/17913 0.0011 0.0099 7
GO:0002366 leukocyte activation involved in immune response 52/877 684/17913 0.0011 0.0099 52
GO:0051937 catecholamine transport 9/877 54/17913 0.0011 0.0100 9
GO:0070206 protein trimerization 9/877 54/17913 0.0011 0.0100 9
GO:0099132 ATP hydrolysis coupled cation transmembrane transport 9/877 54/17913 0.0011 0.0100 9
GO:1904645 response to amyloid-beta 9/877 54/17913 0.0011 0.0100 9
GO:0030218 erythrocyte differentiation 14/877 112/17913 0.0011 0.0100 14
GO:0060419 heart growth 14/877 112/17913 0.0011 0.0100 14

B (565 terms)

ID Description GeneRatio BgRatio pvalue p.adjust Count
GO:0006259 DNA metabolic process 90/588 964/17913 0.0000 0.0000 90
GO:0002366 leukocyte activation involved in immune response 73/588 684/17913 0.0000 0.0000 73
GO:0002263 cell activation involved in immune response 73/588 688/17913 0.0000 0.0000 73
GO:0000278 mitotic cell cycle 86/588 934/17913 0.0000 0.0000 86
GO:0010948 negative regulation of cell cycle process 49/588 344/17913 0.0000 0.0000 49
GO:1903047 mitotic cell cycle process 78/588 816/17913 0.0000 0.0000 78
GO:0044419 interspecies interaction between organisms 84/588 928/17913 0.0000 0.0000 84
GO:0044403 symbiont process 81/588 884/17913 0.0000 0.0000 81
GO:0002443 leukocyte mediated immunity 77/588 814/17913 0.0000 0.0000 77
GO:0016032 viral process 77/588 822/17913 0.0000 0.0000 77
GO:0002274 myeloid leukocyte activation 67/588 652/17913 0.0000 0.0000 67
GO:0036230 granulocyte activation 57/588 506/17913 0.0000 0.0000 57
GO:0002275 myeloid cell activation involved in immune response 59/588 542/17913 0.0000 0.0000 59
GO:0045055 regulated exocytosis 72/588 768/17913 0.0000 0.0000 72
GO:0042119 neutrophil activation 56/588 499/17913 0.0000 0.0000 56
GO:0043299 leukocyte degranulation 58/588 532/17913 0.0000 0.0000 58
GO:0044772 mitotic cell cycle phase transition 60/588 565/17913 0.0000 0.0000 60
GO:0002444 myeloid leukocyte mediated immunity 59/588 549/17913 0.0000 0.0000 59
GO:0044770 cell cycle phase transition 62/588 609/17913 0.0000 0.0000 62
GO:0002283 neutrophil activation involved in immune response 54/588 488/17913 0.0000 0.0000 54
GO:0006887 exocytosis 75/588 862/17913 0.0000 0.0000 75
GO:0043312 neutrophil degranulation 53/588 485/17913 0.0000 0.0000 53
GO:0002446 neutrophil mediated immunity 53/588 499/17913 0.0000 0.0000 53
GO:0010564 regulation of cell cycle process 68/588 764/17913 0.0000 0.0000 68
GO:1903311 regulation of mRNA metabolic process 37/588 275/17913 0.0000 0.0000 37
GO:1901991 negative regulation of mitotic cell cycle phase transition 34/588 235/17913 0.0000 0.0000 34
GO:0045786 negative regulation of cell cycle 58/588 613/17913 0.0000 0.0000 58
GO:0007346 regulation of mitotic cell cycle 58/588 622/17913 0.0000 0.0000 58
GO:0002244 hematopoietic progenitor cell differentiation 27/588 158/17913 0.0000 0.0000 27
GO:1901988 negative regulation of cell cycle phase transition 34/588 254/17913 0.0000 0.0000 34
GO:1901990 regulation of mitotic cell cycle phase transition 45/588 428/17913 0.0000 0.0000 45
GO:0030097 hemopoiesis 68/588 847/17913 0.0000 0.0000 68
GO:0045930 negative regulation of mitotic cell cycle 37/588 308/17913 0.0000 0.0000 37
GO:0016071 mRNA metabolic process 66/588 815/17913 0.0000 0.0000 66
GO:0045087 innate immune response 70/588 893/17913 0.0000 0.0000 70
GO:0033044 regulation of chromosome organization 37/588 311/17913 0.0000 0.0000 37
GO:0002520 immune system development 72/588 938/17913 0.0000 0.0000 72
GO:0060218 hematopoietic stem cell differentiation 19/588 83/17913 0.0000 0.0000 19
GO:1901987 regulation of cell cycle phase transition 46/588 464/17913 0.0000 0.0000 46
GO:0048534 hematopoietic or lymphoid organ development 69/588 890/17913 0.0000 0.0000 69
GO:0006260 DNA replication 33/588 260/17913 0.0000 0.0000 33
GO:1902036 regulation of hematopoietic stem cell differentiation 17/588 72/17913 0.0000 0.0000 17
GO:0019221 cytokine-mediated signaling pathway 61/588 764/17913 0.0000 0.0000 61
GO:0033993 response to lipid 67/588 884/17913 0.0000 0.0000 67
GO:0000122 negative regulation of transcription by RNA polymerase II 59/588 735/17913 0.0000 0.0000 59
GO:0009607 response to biotic stimulus 69/588 938/17913 0.0000 0.0000 69
GO:2001252 positive regulation of chromosome organization 25/588 169/17913 0.0000 0.0000 25
GO:0070198 protein localization to chromosome, telomeric region 11/588 28/17913 0.0000 0.0000 11
GO:1902749 regulation of cell cycle G2/M phase transition 27/588 202/17913 0.0000 0.0000 27
GO:0070482 response to oxygen levels 39/588 389/17913 0.0000 0.0000 39
GO:0000165 MAPK cascade 65/588 882/17913 0.0000 0.0000 65
GO:0023014 signal transduction by protein phosphorylation 65/588 886/17913 0.0000 0.0000 65
GO:2000736 regulation of stem cell differentiation 20/588 116/17913 0.0000 0.0000 20
GO:0002521 leukocyte differentiation 44/588 485/17913 0.0000 0.0000 44
GO:0006974 cellular response to DNA damage stimulus 60/588 791/17913 0.0000 0.0000 60
GO:0000082 G1/S transition of mitotic cell cycle 31/588 269/17913 0.0000 0.0000 31
GO:0042493 response to drug 68/588 958/17913 0.0000 0.0000 68
GO:0051052 regulation of DNA metabolic process 39/588 403/17913 0.0000 0.0000 39
GO:0044839 cell cycle G2/M phase transition 30/588 257/17913 0.0000 0.0000 30
GO:1901532 regulation of hematopoietic progenitor cell differentiation 17/588 85/17913 0.0000 0.0000 17
GO:0001666 response to hypoxia 36/588 354/17913 0.0000 0.0000 36
GO:0010389 regulation of G2/M transition of mitotic cell cycle 25/588 185/17913 0.0000 0.0000 25
GO:0030162 regulation of proteolysis 58/588 762/17913 0.0000 0.0000 58
GO:0044106 cellular amine metabolic process 20/588 121/17913 0.0000 0.0000 20
GO:0019439 aromatic compound catabolic process 52/588 655/17913 0.0000 0.0000 52
GO:0031329 regulation of cellular catabolic process 60/588 814/17913 0.0000 0.0000 60
GO:0043487 regulation of RNA stability 23/588 163/17913 0.0000 0.0000 23
GO:1903405 protein localization to nuclear body 7/588 10/17913 0.0000 0.0000 7
GO:1904851 positive regulation of establishment of protein localization to telomere 7/588 10/17913 0.0000 0.0000 7
GO:1904867 protein localization to Cajal body 7/588 10/17913 0.0000 0.0000 7
GO:0036293 response to decreased oxygen levels 36/588 365/17913 0.0000 0.0000 36
GO:0051054 positive regulation of DNA metabolic process 27/588 222/17913 0.0000 0.0000 27
GO:0051707 response to other organism 64/588 903/17913 0.0000 0.0000 64
GO:0006403 RNA localization 26/588 208/17913 0.0000 0.0000 26
GO:0000086 G2/M transition of mitotic cell cycle 28/588 238/17913 0.0000 0.0000 28
GO:0043207 response to external biotic stimulus 64/588 905/17913 0.0000 0.0000 64
GO:0033238 regulation of cellular amine metabolic process 16/588 80/17913 0.0000 0.0000 16
GO:0000723 telomere maintenance 22/588 154/17913 0.0000 0.0000 22
GO:0009308 amine metabolic process 20/588 128/17913 0.0000 0.0000 20
GO:0044843 cell cycle G1/S phase transition 31/588 288/17913 0.0000 0.0000 31
GO:0034502 protein localization to chromosome 16/588 82/17913 0.0000 0.0000 16
GO:0043488 regulation of mRNA stability 22/588 158/17913 0.0000 0.0000 22
GO:0060249 anatomical structure homeostasis 38/588 413/17913 0.0000 0.0000 38
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 34/588 344/17913 0.0000 0.0000 34
GO:0000398 mRNA splicing, via spliceosome 34/588 344/17913 0.0000 0.0000 34
GO:0070203 regulation of establishment of protein localization to telomere 7/588 11/17913 0.0000 0.0000 7
GO:0071103 DNA conformation change 30/588 279/17913 0.0000 0.0000 30
GO:0050684 regulation of mRNA processing 18/588 108/17913 0.0000 0.0000 18
GO:0046700 heterocycle catabolic process 50/588 641/17913 0.0000 0.0000 50
GO:0044270 cellular nitrogen compound catabolic process 50/588 642/17913 0.0000 0.0000 50
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 16/588 85/17913 0.0000 0.0000 16
GO:0000375 RNA splicing, via transesterification reactions 34/588 348/17913 0.0000 0.0000 34
GO:0019882 antigen processing and presentation 26/588 220/17913 0.0000 0.0000 26
GO:1901361 organic cyclic compound catabolic process 52/588 685/17913 0.0000 0.0000 52
GO:0032392 DNA geometric change 16/588 86/17913 0.0000 0.0000 16
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 15/588 75/17913 0.0000 0.0000 15
GO:0071897 DNA biosynthetic process 24/588 192/17913 0.0000 0.0000 24
GO:0010638 positive regulation of organelle organization 47/588 591/17913 0.0000 0.0000 47
GO:0046649 lymphocyte activation 49/588 630/17913 0.0000 0.0000 49
GO:0017144 drug metabolic process 57/588 792/17913 0.0000 0.0000 57
GO:2000573 positive regulation of DNA biosynthetic process 14/588 66/17913 0.0000 0.0000 14
GO:0042110 T cell activation 39/588 443/17913 0.0000 0.0000 39
GO:0006397 mRNA processing 42/588 499/17913 0.0000 0.0000 42
GO:0051169 nuclear transport 31/588 305/17913 0.0000 0.0000 31
GO:0070202 regulation of establishment of protein localization to chromosome 7/588 12/17913 0.0000 0.0000 7
GO:1904816 positive regulation of protein localization to chromosome, telomeric region 7/588 12/17913 0.0000 0.0000 7
GO:1990173 protein localization to nucleoplasm 7/588 12/17913 0.0000 0.0000 7
GO:0034655 nucleobase-containing compound catabolic process 47/588 598/17913 0.0000 0.0000 47
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 15/588 78/17913 0.0000 0.0000 15
GO:0032200 telomere organization 22/588 167/17913 0.0000 0.0000 22
GO:0070555 response to interleukin-1 23/588 183/17913 0.0000 0.0000 23
GO:0032204 regulation of telomere maintenance 15/588 79/17913 0.0000 0.0000 15
GO:0031145 anaphase-promoting complex-dependent catabolic process 15/588 81/17913 0.0000 0.0000 15
GO:0008380 RNA splicing 38/588 440/17913 0.0000 0.0000 38
GO:0045088 regulation of innate immune response 38/588 440/17913 0.0000 0.0000 38
GO:2000278 regulation of DNA biosynthetic process 17/588 106/17913 0.0000 0.0000 17
GO:0014070 response to organic cyclic compound 60/588 879/17913 0.0000 0.0000 60
GO:0006521 regulation of cellular amino acid metabolic process 13/588 61/17913 0.0000 0.0000 13
GO:1904356 regulation of telomere maintenance via telomere lengthening 13/588 61/17913 0.0000 0.0000 13
GO:0033365 protein localization to organelle 56/588 798/17913 0.0000 0.0000 56
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 16/588 95/17913 0.0000 0.0000 16
GO:0006913 nucleocytoplasmic transport 30/588 302/17913 0.0000 0.0000 30
GO:0048863 stem cell differentiation 26/588 237/17913 0.0000 0.0000 26
GO:0006457 protein folding 22/588 176/17913 0.0000 0.0000 22
GO:0006281 DNA repair 41/588 502/17913 0.0000 0.0000 41
GO:0006325 chromatin organization 52/588 722/17913 0.0000 0.0000 52
GO:0061013 regulation of mRNA catabolic process 22/588 178/17913 0.0000 0.0000 22
GO:0070201 regulation of establishment of protein localization 52/588 723/17913 0.0000 0.0000 52
GO:1902750 negative regulation of cell cycle G2/M phase transition 16/588 97/17913 0.0000 0.0000 16
GO:0050778 positive regulation of immune response 56/588 809/17913 0.0000 0.0000 56
GO:1904814 regulation of protein localization to chromosome, telomeric region 7/588 14/17913 0.0000 0.0000 7
GO:0009894 regulation of catabolic process 61/588 916/17913 0.0000 0.0000 61
GO:0010035 response to inorganic substance 42/588 528/17913 0.0000 0.0000 42
GO:0009314 response to radiation 37/588 435/17913 0.0000 0.0000 37
GO:0062012 regulation of small molecule metabolic process 37/588 439/17913 0.0000 0.0000 37
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 14/588 77/17913 0.0000 0.0000 14
GO:0071347 cellular response to interleukin-1 20/588 156/17913 0.0000 0.0000 20
GO:1904874 positive regulation of telomerase RNA localization to Cajal body 7/588 15/17913 0.0000 0.0000 7
GO:0050821 protein stabilization 21/588 171/17913 0.0000 0.0000 21
GO:1904358 positive regulation of telomere maintenance via telomere lengthening 10/588 37/17913 0.0000 0.0000 10
GO:0007417 central nervous system development 61/588 935/17913 0.0000 0.0000 61
GO:0002220 innate immune response activating cell surface receptor signaling pathway 17/588 116/17913 0.0000 0.0000 17
GO:0010833 telomere maintenance via telomere lengthening 14/588 79/17913 0.0000 0.0000 14
GO:0043069 negative regulation of programmed cell death 60/588 916/17913 0.0000 0.0000 60
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 13/588 69/17913 0.0000 0.0000 13
GO:0031647 regulation of protein stability 27/588 272/17913 0.0000 0.0000 27
GO:0070200 establishment of protein localization to telomere 7/588 16/17913 0.0000 0.0000 7
GO:0002237 response to molecule of bacterial origin 29/588 309/17913 0.0000 0.0000 29
GO:0034622 cellular protein-containing complex assembly 61/588 952/17913 0.0000 0.0000 61
GO:0010243 response to organonitrogen compound 60/588 932/17913 0.0000 0.0000 60
GO:0032880 regulation of protein localization 62/588 979/17913 0.0000 0.0000 62
GO:0030155 regulation of cell adhesion 47/588 659/17913 0.0000 0.0000 47
GO:0090407 organophosphate biosynthetic process 46/588 640/17913 0.0000 0.0000 46
GO:0045597 positive regulation of cell differentiation 61/588 962/17913 0.0000 0.0000 61
GO:0045862 positive regulation of proteolysis 30/588 333/17913 0.0000 0.0000 30
GO:0032206 positive regulation of telomere maintenance 11/588 51/17913 0.0000 0.0000 11
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 17/588 124/17913 0.0000 0.0000 17
GO:0009725 response to hormone 59/588 920/17913 0.0000 0.0000 59
GO:0002764 immune response-regulating signaling pathway 44/588 603/17913 0.0000 0.0000 44
GO:0006352 DNA-templated transcription, initiation 24/588 231/17913 0.0000 0.0000 24
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 24/588 232/17913 0.0000 0.0000 24
GO:0007568 aging 29/588 318/17913 0.0000 0.0000 29
GO:0006278 RNA-dependent DNA biosynthetic process 13/588 74/17913 0.0000 0.0000 13
GO:0002253 activation of immune response 46/588 647/17913 0.0000 0.0000 46
GO:0002218 activation of innate immune response 29/588 319/17913 0.0000 0.0000 29
GO:1903706 regulation of hemopoiesis 37/588 468/17913 0.0000 0.0000 37
GO:0002223 stimulatory C-type lectin receptor signaling pathway 16/588 113/17913 0.0000 0.0000 16
GO:0048024 regulation of mRNA splicing, via spliceosome 13/588 75/17913 0.0000 0.0000 13
GO:1904872 regulation of telomerase RNA localization to Cajal body 7/588 18/17913 0.0000 0.0000 7
GO:0032210 regulation of telomere maintenance via telomerase 11/588 53/17913 0.0000 0.0000 11
GO:0002576 platelet degranulation 17/588 128/17913 0.0000 0.0000 17
GO:0002768 immune response-regulating cell surface receptor signaling pathway 35/588 434/17913 0.0000 0.0000 35
GO:0070498 interleukin-1-mediated signaling pathway 15/588 101/17913 0.0000 0.0000 15
GO:0032212 positive regulation of telomere maintenance via telomerase 9/588 34/17913 0.0000 0.0000 9
GO:0071453 cellular response to oxygen levels 24/588 237/17913 0.0000 0.0000 24
GO:0009165 nucleotide biosynthetic process 31/588 360/17913 0.0000 0.0000 31
GO:0071478 cellular response to radiation 20/588 173/17913 0.0000 0.0000 20
GO:0043484 regulation of RNA splicing 16/588 115/17913 0.0000 0.0000 16
GO:0052547 regulation of peptidase activity 33/588 398/17913 0.0000 0.0000 33
GO:0002478 antigen processing and presentation of exogenous peptide antigen 20/588 174/17913 0.0000 0.0000 20
GO:0035690 cellular response to drug 31/588 362/17913 0.0000 0.0000 31
GO:1902807 negative regulation of cell cycle G1/S phase transition 17/588 130/17913 0.0000 0.0000 17
GO:0035567 non-canonical Wnt signaling pathway 18/588 145/17913 0.0000 0.0000 18
GO:0071214 cellular response to abiotic stimulus 28/588 310/17913 0.0000 0.0000 28
GO:0104004 cellular response to environmental stimulus 28/588 310/17913 0.0000 0.0000 28
GO:0050851 antigen receptor-mediated signaling pathway 23/588 224/17913 0.0000 0.0000 23
GO:1901699 cellular response to nitrogen compound 44/588 620/17913 0.0000 0.0000 44
GO:0019884 antigen processing and presentation of exogenous antigen 20/588 176/17913 0.0000 0.0000 20
GO:0090670 RNA localization to Cajal body 7/588 19/17913 0.0000 0.0000 7
GO:0090671 telomerase RNA localization to Cajal body 7/588 19/17913 0.0000 0.0000 7
GO:0090672 telomerase RNA localization 7/588 19/17913 0.0000 0.0000 7
GO:0090685 RNA localization to nucleus 7/588 19/17913 0.0000 0.0000 7
GO:1901293 nucleoside phosphate biosynthetic process 31/588 365/17913 0.0000 0.0000 31
GO:0042180 cellular ketone metabolic process 24/588 241/17913 0.0000 0.0000 24
GO:0007004 telomere maintenance via telomerase 12/588 67/17913 0.0000 0.0000 12
GO:0071456 cellular response to hypoxia 22/588 210/17913 0.0000 0.0000 22
GO:0034599 cellular response to oxidative stress 27/588 296/17913 0.0000 0.0000 27
GO:0043900 regulation of multi-organism process 33/588 408/17913 0.0000 0.0001 33
GO:0008284 positive regulation of cell proliferation 58/588 931/17913 0.0000 0.0001 58
GO:0009617 response to bacterium 42/588 588/17913 0.0000 0.0001 42
GO:0060071 Wnt signaling pathway, planar cell polarity pathway 15/588 107/17913 0.0000 0.0001 15
GO:0010720 positive regulation of cell development 39/588 528/17913 0.0000 0.0001 39
GO:0006353 DNA-templated transcription, termination 12/588 69/17913 0.0000 0.0001 12
GO:0045089 positive regulation of innate immune response 31/588 373/17913 0.0000 0.0001 31
GO:0045936 negative regulation of phosphate metabolic process 41/588 573/17913 0.0000 0.0001 41
GO:0043066 negative regulation of apoptotic process 56/588 894/17913 0.0000 0.0001 56
GO:0001736 establishment of planar polarity 16/588 123/17913 0.0000 0.0001 16
GO:0007164 establishment of tissue polarity 16/588 123/17913 0.0000 0.0001 16
GO:0090175 regulation of establishment of planar polarity 15/588 109/17913 0.0000 0.0001 15
GO:0042063 gliogenesis 26/588 285/17913 0.0000 0.0001 26
GO:0010563 negative regulation of phosphorus metabolic process 41/588 574/17913 0.0000 0.0001 41
GO:0051301 cell division 41/588 575/17913 0.0000 0.0001 41
GO:0050769 positive regulation of neurogenesis 35/588 455/17913 0.0000 0.0001 35
GO:0071396 cellular response to lipid 41/588 576/17913 0.0000 0.0001 41
GO:0002573 myeloid leukocyte differentiation 21/588 201/17913 0.0000 0.0001 21
GO:0009887 animal organ morphogenesis 60/588 989/17913 0.0000 0.0001 60
GO:0070661 leukocyte proliferation 25/588 270/17913 0.0000 0.0001 25
GO:0002429 immune response-activating cell surface receptor signaling pathway 32/588 399/17913 0.0000 0.0001 32
GO:0051338 regulation of transferase activity 56/588 903/17913 0.0000 0.0001 56
GO:0036294 cellular response to decreased oxygen levels 22/588 220/17913 0.0000 0.0001 22
GO:0009611 response to wounding 45/588 665/17913 0.0000 0.0001 45
GO:0050792 regulation of viral process 21/588 204/17913 0.0000 0.0001 21
GO:0048002 antigen processing and presentation of peptide antigen 20/588 188/17913 0.0000 0.0001 20
GO:0006091 generation of precursor metabolites and energy 37/588 502/17913 0.0000 0.0001 37
GO:0060341 regulation of cellular localization 54/588 863/17913 0.0000 0.0001 54
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 28/588 328/17913 0.0000 0.0001 28
GO:0006520 cellular amino acid metabolic process 29/588 347/17913 0.0000 0.0001 29
GO:0080135 regulation of cellular response to stress 47/588 713/17913 0.0000 0.0001 47
GO:0043062 extracellular structure organization 31/588 387/17913 0.0000 0.0001 31
GO:0006401 RNA catabolic process 30/588 368/17913 0.0000 0.0001 30
GO:0002757 immune response-activating signal transduction 40/588 567/17913 0.0000 0.0001 40
GO:0010212 response to ionizing radiation 17/588 144/17913 0.0000 0.0001 17
GO:0032496 response to lipopolysaccharide 26/588 295/17913 0.0000 0.0001 26
GO:0043620 regulation of DNA-templated transcription in response to stress 15/588 115/17913 0.0000 0.0001 15
GO:0016579 protein deubiquitination 24/588 260/17913 0.0000 0.0001 24
GO:0006261 DNA-dependent DNA replication 16/588 130/17913 0.0000 0.0001 16
GO:0016999 antibiotic metabolic process 16/588 130/17913 0.0000 0.0001 16
GO:0051050 positive regulation of transport 57/588 942/17913 0.0000 0.0001 57
GO:0002758 innate immune response-activating signal transduction 26/588 298/17913 0.0000 0.0001 26
GO:0071241 cellular response to inorganic substance 20/588 194/17913 0.0000 0.0001 20
GO:0006367 transcription initiation from RNA polymerase II promoter 19/588 178/17913 0.0000 0.0001 19
GO:0006418 tRNA aminoacylation for protein translation 9/588 42/17913 0.0000 0.0002 9
GO:0051236 establishment of RNA localization 19/588 179/17913 0.0000 0.0002 19
GO:0009124 nucleoside monophosphate biosynthetic process 20/588 196/17913 0.0000 0.0002 20
GO:0050852 T cell receptor signaling pathway 19/588 180/17913 0.0000 0.0002 19
GO:0051345 positive regulation of hydrolase activity 45/588 684/17913 0.0000 0.0002 45
GO:0034614 cellular response to reactive oxygen species 18/588 165/17913 0.0000 0.0002 18
GO:0008334 histone mRNA metabolic process 7/588 24/17913 0.0000 0.0002 7
GO:0070199 establishment of protein localization to chromosome 7/588 24/17913 0.0000 0.0002 7
GO:0051962 positive regulation of nervous system development 37/588 519/17913 0.0000 0.0002 37
GO:2000027 regulation of animal organ morphogenesis 23/588 250/17913 0.0000 0.0002 23
GO:0010942 positive regulation of cell death 46/588 710/17913 0.0000 0.0002 46
GO:0044283 small molecule biosynthetic process 47/588 732/17913 0.0000 0.0002 47
GO:0043408 regulation of MAPK cascade 45/588 689/17913 0.0000 0.0002 45
GO:0048511 rhythmic process 25/588 287/17913 0.0000 0.0002 25
GO:0030217 T cell differentiation 22/588 234/17913 0.0000 0.0002 22
GO:0030098 lymphocyte differentiation 27/588 325/17913 0.0000 0.0002 27
GO:0010332 response to gamma radiation 10/588 55/17913 0.0000 0.0002 10
GO:0007623 circadian rhythm 20/588 201/17913 0.0000 0.0002 20
GO:0007420 brain development 45/588 694/17913 0.0000 0.0002 45
GO:0043065 positive regulation of apoptotic process 43/588 652/17913 0.0000 0.0002 43
GO:0070997 neuron death 28/588 347/17913 0.0000 0.0002 28
GO:0055086 nucleobase-containing small molecule metabolic process 47/588 740/17913 0.0000 0.0002 47
GO:0070646 protein modification by small protein removal 24/588 273/17913 0.0000 0.0002 24
GO:0009117 nucleotide metabolic process 43/588 654/17913 0.0000 0.0002 43
GO:0043039 tRNA aminoacylation 9/588 45/17913 0.0000 0.0003 9
GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 14/588 109/17913 0.0000 0.0003 14
GO:0001738 morphogenesis of a polarized epithelium 16/588 139/17913 0.0000 0.0003 16
GO:1903827 regulation of cellular protein localization 36/588 509/17913 0.0000 0.0003 36
GO:2001251 negative regulation of chromosome organization 15/588 125/17913 0.0000 0.0003 15
GO:0034504 protein localization to nucleus 21/588 223/17913 0.0000 0.0003 21
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 25/588 295/17913 0.0000 0.0003 25
GO:0043038 amino acid activation 9/588 46/17913 0.0000 0.0003 9
GO:0043068 positive regulation of programmed cell death 43/588 660/17913 0.0000 0.0003 43
GO:0038093 Fc receptor signaling pathway 22/588 241/17913 0.0000 0.0003 22
GO:0030198 extracellular matrix organization 27/588 334/17913 0.0000 0.0003 27
GO:0045787 positive regulation of cell cycle 29/588 373/17913 0.0000 0.0003 29
GO:0006753 nucleoside phosphate metabolic process 43/588 663/17913 0.0000 0.0003 43
GO:0035966 response to topologically incorrect protein 18/588 175/17913 0.0000 0.0004 18
GO:0046651 lymphocyte proliferation 22/588 244/17913 0.0000 0.0004 22
GO:0042326 negative regulation of phosphorylation 33/588 455/17913 0.0000 0.0004 33
GO:0045732 positive regulation of protein catabolic process 19/588 192/17913 0.0000 0.0004 19
GO:0071417 cellular response to organonitrogen compound 38/588 559/17913 0.0000 0.0004 38
GO:0071482 cellular response to light stimulus 14/588 113/17913 0.0000 0.0004 14
GO:0050657 nucleic acid transport 18/588 176/17913 0.0000 0.0004 18
GO:0050658 RNA transport 18/588 176/17913 0.0000 0.0004 18
GO:0044087 regulation of cellular component biogenesis 53/588 891/17913 0.0000 0.0004 53
GO:0072331 signal transduction by p53 class mediator 23/588 264/17913 0.0000 0.0004 23
GO:0032943 mononuclear cell proliferation 22/588 246/17913 0.0000 0.0004 22
GO:1903364 positive regulation of cellular protein catabolic process 15/588 129/17913 0.0000 0.0004 15
GO:2000045 regulation of G1/S transition of mitotic cell cycle 18/588 177/17913 0.0000 0.0004 18
GO:0032069 regulation of nuclease activity 6/588 19/17913 0.0000 0.0004 6
GO:0010565 regulation of cellular ketone metabolic process 18/588 178/17913 0.0000 0.0004 18
GO:1904951 positive regulation of establishment of protein localization 32/588 440/17913 0.0000 0.0004 32
GO:0060322 head development 46/588 738/17913 0.0000 0.0004 46
GO:0000302 response to reactive oxygen species 21/588 230/17913 0.0000 0.0004 21
GO:1903362 regulation of cellular protein catabolic process 21/588 230/17913 0.0000 0.0004 21
GO:0051095 regulation of helicase activity 5/588 12/17913 0.0000 0.0004 5
GO:0006979 response to oxidative stress 32/588 442/17913 0.0000 0.0005 32
GO:0010498 proteasomal protein catabolic process 29/588 382/17913 0.0000 0.0005 29
GO:0032922 circadian regulation of gene expression 10/588 61/17913 0.0000 0.0005 10
GO:0043902 positive regulation of multi-organism process 18/588 180/17913 0.0000 0.0005 18
GO:0001817 regulation of cytokine production 44/588 698/17913 0.0000 0.0005 44
GO:0006275 regulation of DNA replication 13/588 102/17913 0.0000 0.0005 13
GO:0006289 nucleotide-excision repair 13/588 102/17913 0.0000 0.0005 13
GO:1905330 regulation of morphogenesis of an epithelium 18/588 181/17913 0.0000 0.0005 18
GO:0048524 positive regulation of viral process 13/588 103/17913 0.0000 0.0005 13
GO:0001934 positive regulation of protein phosphorylation 53/588 907/17913 0.0000 0.0006 53
GO:0031347 regulation of defense response 52/588 885/17913 0.0000 0.0006 52
GO:0098781 ncRNA transcription 13/588 104/17913 0.0000 0.0006 13
GO:0032508 DNA duplex unwinding 11/588 76/17913 0.0000 0.0006 11
GO:0061136 regulation of proteasomal protein catabolic process 17/588 167/17913 0.0000 0.0006 17
GO:0050764 regulation of phagocytosis 12/588 90/17913 0.0000 0.0006 12
GO:0031349 positive regulation of defense response 35/588 512/17913 0.0000 0.0006 35
GO:0009266 response to temperature stimulus 20/588 219/17913 0.0000 0.0006 20
GO:0052548 regulation of endopeptidase activity 28/588 370/17913 0.0000 0.0006 28
GO:0030099 myeloid cell differentiation 30/588 411/17913 0.0000 0.0007 30
GO:1901214 regulation of neuron death 25/588 313/17913 0.0000 0.0007 25
GO:0006270 DNA replication initiation 7/588 30/17913 0.0000 0.0007 7
GO:0015931 nucleobase-containing compound transport 20/588 221/17913 0.0000 0.0007 20
GO:0071826 ribonucleoprotein complex subunit organization 20/588 221/17913 0.0000 0.0007 20
GO:0006354 DNA-templated transcription, elongation 13/588 106/17913 0.0000 0.0007 13
GO:0008584 male gonad development 15/588 137/17913 0.0000 0.0007 15
GO:0009411 response to UV 15/588 137/17913 0.0000 0.0007 15
GO:0071824 protein-DNA complex subunit organization 21/588 240/17913 0.0000 0.0007 21
GO:0042176 regulation of protein catabolic process 27/588 354/17913 0.0000 0.0007 27
GO:0070317 negative regulation of G0 to G1 transition 8/588 41/17913 0.0000 0.0008 8
GO:0031056 regulation of histone modification 15/588 138/17913 0.0000 0.0008 15
GO:0046546 development of primary male sexual characteristics 15/588 138/17913 0.0000 0.0008 15
GO:0009636 response to toxic substance 34/588 499/17913 0.0001 0.0008 34
GO:1901800 positive regulation of proteasomal protein catabolic process 12/588 93/17913 0.0001 0.0008 12
GO:0006368 transcription elongation from RNA polymerase II promoter 11/588 79/17913 0.0001 0.0008 11
GO:0043549 regulation of kinase activity 48/588 808/17913 0.0001 0.0008 48
GO:0040007 growth 54/588 948/17913 0.0001 0.0009 54
GO:0051347 positive regulation of transferase activity 39/588 609/17913 0.0001 0.0009 39
GO:0001816 cytokine production 46/588 765/17913 0.0001 0.0009 46
GO:0006310 DNA recombination 21/588 244/17913 0.0001 0.0009 21
GO:0033151 V(D)J recombination 5/588 14/17913 0.0001 0.0009 5
GO:0006518 peptide metabolic process 48/588 811/17913 0.0001 0.0009 48
GO:0002440 production of molecular mediator of immune response 18/588 191/17913 0.0001 0.0009 18
GO:0051170 import into nucleus 14/588 125/17913 0.0001 0.0010 14
GO:0022618 ribonucleoprotein complex assembly 19/588 209/17913 0.0001 0.0010 19
GO:0019725 cellular homeostasis 48/588 814/17913 0.0001 0.0010 48
GO:0002285 lymphocyte activation involved in immune response 16/588 158/17913 0.0001 0.0010 16
GO:0065004 protein-DNA complex assembly 19/588 210/17913 0.0001 0.0010 19
GO:0042327 positive regulation of phosphorylation 54/588 955/17913 0.0001 0.0010 54
GO:0097327 response to antineoplastic agent 12/588 96/17913 0.0001 0.0011 12
GO:2000377 regulation of reactive oxygen species metabolic process 18/588 194/17913 0.0001 0.0011 18
GO:1902806 regulation of cell cycle G1/S phase transition 18/588 195/17913 0.0001 0.0012 18
GO:1903312 negative regulation of mRNA metabolic process 10/588 69/17913 0.0001 0.0012 10
GO:0030163 protein catabolic process 47/588 799/17913 0.0001 0.0012 47
GO:0006986 response to unfolded protein 16/588 161/17913 0.0001 0.0012 16
GO:0009416 response to light stimulus 24/588 307/17913 0.0001 0.0012 24
GO:0038061 NIK/NF-kappaB signaling 17/588 179/17913 0.0001 0.0013 17
GO:0045859 regulation of protein kinase activity 44/588 733/17913 0.0001 0.0013 44
GO:0045785 positive regulation of cell adhesion 28/588 388/17913 0.0001 0.0013 28
GO:0046677 response to antibiotic 25/588 328/17913 0.0001 0.0013 25
GO:0042113 B cell activation 19/588 215/17913 0.0001 0.0013 19
GO:0044786 cell cycle DNA replication 9/588 57/17913 0.0001 0.0013 9
GO:0022407 regulation of cell-cell adhesion 28/588 389/17913 0.0001 0.0013 28
GO:0009123 nucleoside monophosphate metabolic process 26/588 349/17913 0.0001 0.0014 26
GO:0070316 regulation of G0 to G1 transition 8/588 45/17913 0.0001 0.0014 8
GO:0016571 histone methylation 14/588 130/17913 0.0001 0.0014 14
GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 18/588 198/17913 0.0001 0.0014 18
GO:0001101 response to acid chemical 25/588 330/17913 0.0001 0.0014 25
GO:0032870 cellular response to hormone stimulus 40/588 647/17913 0.0001 0.0014 40
GO:0044257 cellular protein catabolic process 40/588 648/17913 0.0001 0.0014 40
GO:0002449 lymphocyte mediated immunity 23/588 293/17913 0.0001 0.0015 23
GO:1902275 regulation of chromatin organization 16/588 165/17913 0.0001 0.0016 16
GO:0061614 pri-miRNA transcription by RNA polymerase II 8/588 46/17913 0.0001 0.0016 8
GO:0009991 response to extracellular stimulus 33/588 498/17913 0.0001 0.0016 33
GO:0007569 cell aging 13/588 116/17913 0.0001 0.0016 13
GO:1901998 toxin transport 7/588 35/17913 0.0001 0.0017 7
GO:0006220 pyrimidine nucleotide metabolic process 9/588 59/17913 0.0001 0.0017 9
GO:0048545 response to steroid hormone 27/588 375/17913 0.0001 0.0017 27
GO:0043632 modification-dependent macromolecule catabolic process 34/588 522/17913 0.0001 0.0017 34
GO:0010038 response to metal ion 25/588 335/17913 0.0001 0.0017 25
GO:0006283 transcription-coupled nucleotide-excision repair 10/588 73/17913 0.0001 0.0018 10
GO:0033260 nuclear DNA replication 8/588 47/17913 0.0001 0.0018 8
GO:0045023 G0 to G1 transition 8/588 47/17913 0.0001 0.0018 8
GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 9/588 60/17913 0.0001 0.0019 9
GO:0016444 somatic cell DNA recombination 9/588 60/17913 0.0001 0.0019 9
GO:0050766 positive regulation of phagocytosis 9/588 60/17913 0.0001 0.0019 9
GO:0006402 mRNA catabolic process 25/588 338/17913 0.0001 0.0019 25
GO:0090263 positive regulation of canonical Wnt signaling pathway 14/588 135/17913 0.0001 0.0019 14
GO:0006479 protein methylation 16/588 169/17913 0.0001 0.0020 16
GO:0008213 protein alkylation 16/588 169/17913 0.0001 0.0020 16
GO:0038095 Fc-epsilon receptor signaling pathway 16/588 169/17913 0.0001 0.0020 16
GO:0032481 positive regulation of type I interferon production 10/588 74/17913 0.0001 0.0020 10
GO:0002009 morphogenesis of an epithelium 34/588 527/17913 0.0001 0.0020 34
GO:0043687 post-translational protein modification 26/588 360/17913 0.0002 0.0021 26
GO:0044089 positive regulation of cellular component biogenesis 33/588 507/17913 0.0002 0.0021 33
GO:0071216 cellular response to biotic stimulus 18/588 206/17913 0.0002 0.0021 18
GO:0060284 regulation of cell development 50/588 893/17913 0.0002 0.0022 50
GO:0097435 supramolecular fiber organization 35/588 553/17913 0.0002 0.0023 35
GO:0006511 ubiquitin-dependent protein catabolic process 33/588 510/17913 0.0002 0.0023 33
GO:0071407 cellular response to organic cyclic compound 34/588 533/17913 0.0002 0.0024 34
GO:0031960 response to corticosteroid 15/588 155/17913 0.0002 0.0024 15
GO:0046390 ribose phosphate biosynthetic process 22/588 284/17913 0.0002 0.0024 22
GO:1903409 reactive oxygen species biosynthetic process 13/588 122/17913 0.0002 0.0024 13
GO:0019058 viral life cycle 24/588 324/17913 0.0002 0.0024 24
GO:0045861 negative regulation of proteolysis 24/588 324/17913 0.0002 0.0024 24
GO:1901652 response to peptide 32/588 491/17913 0.0002 0.0025 32
GO:0050865 regulation of cell activation 34/588 535/17913 0.0002 0.0025 34
GO:0051384 response to glucocorticoid 14/588 139/17913 0.0002 0.0025 14
GO:0050686 negative regulation of mRNA processing 6/588 27/17913 0.0002 0.0026 6
GO:0032479 regulation of type I interferon production 13/588 123/17913 0.0002 0.0026 13
GO:0034644 cellular response to UV 10/588 77/17913 0.0002 0.0026 10
GO:0032873 negative regulation of stress-activated MAPK cascade 8/588 50/17913 0.0002 0.0026 8
GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 8/588 50/17913 0.0002 0.0026 8
GO:0009162 deoxyribonucleoside monophosphate metabolic process 4/588 10/17913 0.0002 0.0026 4
GO:0019941 modification-dependent protein catabolic process 33/588 515/17913 0.0002 0.0026 33
GO:0072594 establishment of protein localization to organelle 30/588 452/17913 0.0002 0.0028 30
GO:0046782 regulation of viral transcription 9/588 64/17913 0.0002 0.0029 9
GO:0072593 reactive oxygen species metabolic process 21/588 269/17913 0.0002 0.0029 21
GO:0006323 DNA packaging 17/588 194/17913 0.0002 0.0029 17
GO:0048146 positive regulation of fibroblast proliferation 8/588 51/17913 0.0002 0.0029 8
GO:0097366 response to bronchodilator 8/588 51/17913 0.0002 0.0029 8
GO:0032606 type I interferon production 13/588 125/17913 0.0002 0.0030 13
GO:0034968 histone lysine methylation 12/588 109/17913 0.0002 0.0030 12
GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 12/588 109/17913 0.0002 0.0030 12
GO:0050767 regulation of neurogenesis 44/588 768/17913 0.0002 0.0031 44
GO:0042098 T cell proliferation 16/588 177/17913 0.0002 0.0031 16
GO:0051223 regulation of protein transport 40/588 677/17913 0.0003 0.0031 40
GO:0048709 oligodendrocyte differentiation 11/588 94/17913 0.0003 0.0031 11
GO:0050878 regulation of body fluid levels 32/588 499/17913 0.0003 0.0031 32
GO:0072522 purine-containing compound biosynthetic process 22/588 291/17913 0.0003 0.0031 22
GO:0046661 male sex differentiation 15/588 160/17913 0.0003 0.0031 15
GO:0098727 maintenance of cell number 15/588 160/17913 0.0003 0.0031 15
GO:0032989 cellular component morphogenesis 52/588 960/17913 0.0003 0.0033 52
GO:0051603 proteolysis involved in cellular protein catabolic process 36/588 590/17913 0.0003 0.0034 36
GO:0034976 response to endoplasmic reticulum stress 20/588 254/17913 0.0003 0.0035 20
GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II 7/588 40/17913 0.0003 0.0035 7
GO:0090087 regulation of peptide transport 41/588 706/17913 0.0003 0.0036 41
GO:0009262 deoxyribonucleotide metabolic process 6/588 29/17913 0.0003 0.0036 6
GO:0008406 gonad development 18/588 217/17913 0.0003 0.0036 18
GO:0030968 endoplasmic reticulum unfolded protein response 12/588 112/17913 0.0003 0.0037 12
GO:1903037 regulation of leukocyte cell-cell adhesion 22/588 295/17913 0.0003 0.0037 22
GO:0019042 viral latency 4/588 11/17913 0.0003 0.0038 4
GO:0007599 hemostasis 24/588 336/17913 0.0003 0.0038 24
GO:0042060 wound healing 34/588 550/17913 0.0003 0.0038 34
GO:0002697 regulation of immune effector process 29/588 441/17913 0.0003 0.0038 29
GO:0002200 somatic diversification of immune receptors 9/588 67/17913 0.0003 0.0038 9
GO:0055114 oxidation-reduction process 51/588 944/17913 0.0003 0.0039 51
GO:0006935 chemotaxis 34/588 551/17913 0.0003 0.0039 34
GO:0050434 positive regulation of viral transcription 7/588 41/17913 0.0003 0.0039 7
GO:0051402 neuron apoptotic process 19/588 238/17913 0.0003 0.0040 19
GO:0000902 cell morphogenesis 48/588 874/17913 0.0003 0.0040 48
GO:0006970 response to osmotic stress 10/588 82/17913 0.0003 0.0040 10
GO:0032386 regulation of intracellular transport 27/588 400/17913 0.0003 0.0040 27
GO:1903829 positive regulation of cellular protein localization 23/588 318/17913 0.0004 0.0041 23
GO:0042330 taxis 34/588 553/17913 0.0004 0.0041 34
GO:0071219 cellular response to molecule of bacterial origin 16/588 183/17913 0.0004 0.0042 16
GO:0006304 DNA modification 12/588 114/17913 0.0004 0.0042 12
GO:0002377 immunoglobulin production 11/588 98/17913 0.0004 0.0042 11
GO:0031667 response to nutrient levels 30/588 466/17913 0.0004 0.0042 30
GO:0010543 regulation of platelet activation 6/588 30/17913 0.0004 0.0042 6
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II 6/588 30/17913 0.0004 0.0042 6
GO:0019216 regulation of lipid metabolic process 27/588 402/17913 0.0004 0.0042 27
GO:0002320 lymphoid progenitor cell differentiation 5/588 20/17913 0.0004 0.0044 5
GO:0048872 homeostasis of number of cells 19/588 241/17913 0.0004 0.0045 19
GO:0033077 T cell differentiation in thymus 9/588 69/17913 0.0004 0.0046 9
GO:0033209 tumor necrosis factor-mediated signaling pathway 15/588 167/17913 0.0004 0.0046 15
GO:0071248 cellular response to metal ion 15/588 167/17913 0.0004 0.0046 15
GO:0048608 reproductive structure development 28/588 426/17913 0.0004 0.0046 28
GO:0045137 development of primary sexual characteristics 18/588 223/17913 0.0004 0.0047 18
GO:1901653 cellular response to peptide 25/588 364/17913 0.0004 0.0049 25
GO:0009615 response to virus 23/588 323/17913 0.0004 0.0050 23
GO:0006369 termination of RNA polymerase II transcription 6/588 31/17913 0.0004 0.0050 6
GO:0048871 multicellular organismal homeostasis 30/588 472/17913 0.0005 0.0051 30
GO:0061458 reproductive system development 28/588 429/17913 0.0005 0.0051 28
GO:0031330 negative regulation of cellular catabolic process 19/588 244/17913 0.0005 0.0051 19
GO:1900180 regulation of protein localization to nucleus 12/588 117/17913 0.0005 0.0051 12
GO:0090090 negative regulation of canonical Wnt signaling pathway 15/588 169/17913 0.0005 0.0051 15
GO:0034612 response to tumor necrosis factor 21/588 284/17913 0.0005 0.0052 21
GO:0009156 ribonucleoside monophosphate biosynthetic process 16/588 188/17913 0.0005 0.0053 16
GO:0007063 regulation of sister chromatid cohesion 5/588 21/17913 0.0005 0.0054 5
GO:0030177 positive regulation of Wnt signaling pathway 15/588 170/17913 0.0005 0.0054 15
GO:0035967 cellular response to topologically incorrect protein 13/588 135/17913 0.0005 0.0055 13
GO:0045576 mast cell activation 8/588 57/17913 0.0005 0.0056 8
GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint 8/588 57/17913 0.0005 0.0056 8
GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint 8/588 57/17913 0.0005 0.0056 8
GO:0071356 cellular response to tumor necrosis factor 20/588 266/17913 0.0005 0.0056 20
GO:0071346 cellular response to interferon-gamma 14/588 153/17913 0.0005 0.0057 14
GO:0030851 granulocyte differentiation 6/588 32/17913 0.0005 0.0057 6
GO:0009267 cellular response to starvation 13/588 136/17913 0.0005 0.0058 13
GO:0007159 leukocyte cell-cell adhesion 23/588 328/17913 0.0006 0.0059 23
GO:0048729 tissue morphogenesis 37/588 635/17913 0.0006 0.0060 37
GO:0001659 temperature homeostasis 15/588 172/17913 0.0006 0.0060 15
GO:0035019 somatic stem cell population maintenance 9/588 72/17913 0.0006 0.0060 9
GO:1901654 response to ketone 16/588 191/17913 0.0006 0.0062 16
GO:0071900 regulation of protein serine/threonine kinase activity 30/588 479/17913 0.0006 0.0062 30
GO:0019079 viral genome replication 12/588 120/17913 0.0006 0.0062 12
GO:0009790 embryo development 51/588 968/17913 0.0006 0.0062 51
GO:0061024 membrane organization 41/588 730/17913 0.0006 0.0063 41
GO:0034341 response to interferon-gamma 15/588 173/17913 0.0006 0.0063 15
GO:0002286 T cell activation involved in immune response 10/588 88/17913 0.0006 0.0064 10
GO:0002456 T cell mediated immunity 10/588 88/17913 0.0006 0.0064 10
GO:0031058 positive regulation of histone modification 10/588 88/17913 0.0006 0.0064 10
GO:0048714 positive regulation of oligodendrocyte differentiation 5/588 22/17913 0.0006 0.0065 5
GO:0007596 blood coagulation 23/588 331/17913 0.0006 0.0065 23
GO:0009410 response to xenobiotic stimulus 20/588 270/17913 0.0006 0.0065 20
GO:0010001 glial cell differentiation 17/588 212/17913 0.0007 0.0067 17
GO:0072413 signal transduction involved in mitotic cell cycle checkpoint 8/588 59/17913 0.0007 0.0067 8
GO:1902402 signal transduction involved in mitotic DNA damage checkpoint 8/588 59/17913 0.0007 0.0067 8
GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint 8/588 59/17913 0.0007 0.0067 8
GO:0043086 negative regulation of catalytic activity 42/588 757/17913 0.0007 0.0067 42
GO:0031668 cellular response to extracellular stimulus 19/588 251/17913 0.0007 0.0067 19
GO:0044728 DNA methylation or demethylation 10/588 89/17913 0.0007 0.0068 10
GO:0060968 regulation of gene silencing 13/588 139/17913 0.0007 0.0068 13
GO:0007006 mitochondrial membrane organization 12/588 122/17913 0.0007 0.0069 12
GO:0018022 peptidyl-lysine methylation 12/588 122/17913 0.0007 0.0069 12
GO:0030193 regulation of blood coagulation 9/588 74/17913 0.0007 0.0070 9
GO:1900182 positive regulation of protein localization to nucleus 9/588 74/17913 0.0007 0.0070 9
GO:0045666 positive regulation of neuron differentiation 24/588 355/17913 0.0007 0.0072 24
GO:0051168 nuclear export 15/588 176/17913 0.0007 0.0072 15
GO:0071222 cellular response to lipopolysaccharide 15/588 176/17913 0.0007 0.0072 15
GO:0043200 response to amino acid 11/588 106/17913 0.0007 0.0073 11
GO:0009408 response to heat 14/588 158/17913 0.0007 0.0073 14
GO:0019827 stem cell population maintenance 14/588 158/17913 0.0007 0.0073 14
GO:1903039 positive regulation of leukocyte cell-cell adhesion 17/588 214/17913 0.0007 0.0073 17
GO:0034620 cellular response to unfolded protein 12/588 123/17913 0.0007 0.0073 12
GO:0006412 translation 38/588 668/17913 0.0007 0.0074 38
GO:1900046 regulation of hemostasis 9/588 75/17913 0.0008 0.0076 9
GO:0045807 positive regulation of endocytosis 13/588 141/17913 0.0008 0.0076 13
GO:0007064 mitotic sister chromatid cohesion 5/588 23/17913 0.0008 0.0076 5
GO:2000637 positive regulation of gene silencing by miRNA 5/588 23/17913 0.0008 0.0076 5
GO:0043043 peptide biosynthetic process 39/588 693/17913 0.0008 0.0077 39
GO:0048589 developmental growth 36/588 624/17913 0.0008 0.0078 36
GO:0050817 coagulation 23/588 337/17913 0.0008 0.0078 23
GO:0035821 modification of morphology or physiology of other organism 14/588 160/17913 0.0008 0.0081 14
GO:0042692 muscle cell differentiation 24/588 359/17913 0.0008 0.0081 24
GO:0014015 positive regulation of gliogenesis 9/588 76/17913 0.0008 0.0082 9
GO:0001819 positive regulation of cytokine production 28/588 446/17913 0.0008 0.0083 28
GO:2001022 positive regulation of response to DNA damage stimulus 10/588 92/17913 0.0009 0.0084 10
GO:0007339 binding of sperm to zona pellucida 6/588 35/17913 0.0009 0.0085 6
GO:0045740 positive regulation of DNA replication 6/588 35/17913 0.0009 0.0085 6
GO:0010885 regulation of cholesterol storage 4/588 14/17913 0.0009 0.0086 4
GO:0010952 positive regulation of peptidase activity 15/588 180/17913 0.0009 0.0087 15
GO:0031098 stress-activated protein kinase signaling cascade 20/588 278/17913 0.0009 0.0087 20
GO:0002064 epithelial cell development 16/588 199/17913 0.0009 0.0087 16
GO:0032648 regulation of interferon-beta production 7/588 48/17913 0.0009 0.0087 7
GO:0051972 regulation of telomerase activity 7/588 48/17913 0.0009 0.0087 7
GO:0061647 histone H3-K9 modification 7/588 48/17913 0.0009 0.0087 7
GO:1903727 positive regulation of phospholipid metabolic process 7/588 48/17913 0.0009 0.0087 7
GO:0042542 response to hydrogen peroxide 13/588 144/17913 0.0009 0.0089 13
GO:0098609 cell-cell adhesion 42/588 771/17913 0.0009 0.0089 42
GO:0009260 ribonucleotide biosynthetic process 20/588 279/17913 0.0009 0.0090 20
GO:0060148 positive regulation of posttranscriptional gene silencing 5/588 24/17913 0.0009 0.0090 5
GO:0006164 purine nucleotide biosynthetic process 20/588 280/17913 0.0010 0.0094 20
GO:0002262 myeloid cell homeostasis 13/588 145/17913 0.0010 0.0094 13
GO:2001020 regulation of response to DNA damage stimulus 16/588 201/17913 0.0010 0.0095 16
GO:0043901 negative regulation of multi-organism process 15/588 182/17913 0.0010 0.0095 15
GO:1903708 positive regulation of hemopoiesis 15/588 182/17913 0.0010 0.0095 15
GO:0033674 positive regulation of kinase activity 32/588 541/17913 0.0010 0.0095 32
GO:0031571 mitotic G1 DNA damage checkpoint 8/588 63/17913 0.0010 0.0095 8
GO:0036498 IRE1-mediated unfolded protein response 8/588 63/17913 0.0010 0.0095 8
GO:0044819 mitotic G1/S transition checkpoint 8/588 63/17913 0.0010 0.0095 8
GO:0007229 integrin-mediated signaling pathway 10/588 94/17913 0.0010 0.0095 10
GO:1990823 response to leukemia inhibitory factor 10/588 94/17913 0.0010 0.0095 10
GO:1990830 cellular response to leukemia inhibitory factor 10/588 94/17913 0.0010 0.0095 10
GO:0051973 positive regulation of telomerase activity 6/588 36/17913 0.0010 0.0095 6
GO:0097237 cellular response to toxic substance 18/588 241/17913 0.0010 0.0097 18
GO:1904019 epithelial cell apoptotic process 11/588 111/17913 0.0011 0.0098 11
GO:0043254 regulation of protein complex assembly 26/588 409/17913 0.0011 0.0099 26

C (525 terms)

ID Description GeneRatio BgRatio pvalue p.adjust Count
GO:0002366 leukocyte activation involved in immune response 59/300 684/17913 0.0000 0.0000 59
GO:0002263 cell activation involved in immune response 59/300 688/17913 0.0000 0.0000 59
GO:0002274 myeloid leukocyte activation 56/300 652/17913 0.0000 0.0000 56
GO:0036230 granulocyte activation 48/300 506/17913 0.0000 0.0000 48
GO:0042119 neutrophil activation 47/300 499/17913 0.0000 0.0000 47
GO:0006887 exocytosis 61/300 862/17913 0.0000 0.0000 61
GO:0043299 leukocyte degranulation 48/300 532/17913 0.0000 0.0000 48
GO:0043312 neutrophil degranulation 45/300 485/17913 0.0000 0.0000 45
GO:0045055 regulated exocytosis 56/300 768/17913 0.0000 0.0000 56
GO:0002283 neutrophil activation involved in immune response 45/300 488/17913 0.0000 0.0000 45
GO:0002275 myeloid cell activation involved in immune response 47/300 542/17913 0.0000 0.0000 47
GO:0002446 neutrophil mediated immunity 45/300 499/17913 0.0000 0.0000 45
GO:0002444 myeloid leukocyte mediated immunity 47/300 549/17913 0.0000 0.0000 47
GO:0002443 leukocyte mediated immunity 55/300 814/17913 0.0000 0.0000 55
GO:0019221 cytokine-mediated signaling pathway 46/300 764/17913 0.0000 0.0000 46
GO:0097190 apoptotic signaling pathway 37/300 579/17913 0.0000 0.0000 37
GO:0050865 regulation of cell activation 34/300 535/17913 0.0000 0.0000 34
GO:2001233 regulation of apoptotic signaling pathway 29/300 397/17913 0.0000 0.0000 29
GO:0043066 negative regulation of apoptotic process 45/300 894/17913 0.0000 0.0000 45
GO:0043069 negative regulation of programmed cell death 45/300 916/17913 0.0000 0.0000 45
GO:0001816 cytokine production 40/300 765/17913 0.0000 0.0000 40
GO:0002694 regulation of leukocyte activation 31/300 492/17913 0.0000 0.0000 31
GO:0002520 immune system development 44/300 938/17913 0.0000 0.0000 44
GO:0014070 response to organic cyclic compound 42/300 879/17913 0.0000 0.0000 42
GO:0050867 positive regulation of cell activation 24/300 319/17913 0.0000 0.0000 24
GO:0032870 cellular response to hormone stimulus 35/300 647/17913 0.0000 0.0000 35
GO:0048534 hematopoietic or lymphoid organ development 42/300 890/17913 0.0000 0.0000 42
GO:0001817 regulation of cytokine production 36/300 698/17913 0.0000 0.0000 36
GO:0030097 hemopoiesis 40/300 847/17913 0.0000 0.0000 40
GO:0010942 positive regulation of cell death 36/300 710/17913 0.0000 0.0000 36
GO:0019725 cellular homeostasis 39/300 814/17913 0.0000 0.0000 39
GO:0001818 negative regulation of cytokine production 22/300 290/17913 0.0000 0.0000 22
GO:0043065 positive regulation of apoptotic process 34/300 652/17913 0.0000 0.0000 34
GO:0010035 response to inorganic substance 30/300 528/17913 0.0000 0.0000 30
GO:0043068 positive regulation of programmed cell death 34/300 660/17913 0.0000 0.0000 34
GO:0002285 lymphocyte activation involved in immune response 16/300 158/17913 0.0000 0.0000 16
GO:0009725 response to hormone 41/300 920/17913 0.0000 0.0000 41
GO:0002696 positive regulation of leukocyte activation 22/300 305/17913 0.0000 0.0000 22
GO:0044403 symbiont process 40/300 884/17913 0.0000 0.0000 40
GO:0042493 response to drug 42/300 958/17913 0.0000 0.0000 42
GO:0002700 regulation of production of molecular mediator of immune response 15/300 138/17913 0.0000 0.0000 15
GO:0044419 interspecies interaction between organisms 41/300 928/17913 0.0000 0.0000 41
GO:0046916 cellular transition metal ion homeostasis 12/300 83/17913 0.0000 0.0000 12
GO:0030003 cellular cation homeostasis 29/300 518/17913 0.0000 0.0000 29
GO:0070997 neuron death 23/300 347/17913 0.0000 0.0000 23
GO:0002440 production of molecular mediator of immune response 17/300 191/17913 0.0000 0.0000 17
GO:0006873 cellular ion homeostasis 29/300 531/17913 0.0000 0.0000 29
GO:0046649 lymphocyte activation 32/300 630/17913 0.0000 0.0000 32
GO:0000165 MAPK cascade 39/300 882/17913 0.0000 0.0000 39
GO:0023014 signal transduction by protein phosphorylation 39/300 886/17913 0.0000 0.0000 39
GO:2001234 negative regulation of apoptotic signaling pathway 18/300 223/17913 0.0000 0.0000 18
GO:0002521 leukocyte differentiation 27/300 485/17913 0.0000 0.0000 27
GO:0010038 response to metal ion 22/300 335/17913 0.0000 0.0000 22
GO:0051050 positive regulation of transport 40/300 942/17913 0.0000 0.0000 40
GO:0055080 cation homeostasis 30/300 588/17913 0.0000 0.0000 30
GO:0040007 growth 40/300 948/17913 0.0000 0.0000 40
GO:0030155 regulation of cell adhesion 32/300 659/17913 0.0000 0.0000 32
GO:1901214 regulation of neuron death 21/300 313/17913 0.0000 0.0000 21
GO:0051249 regulation of lymphocyte activation 24/300 401/17913 0.0000 0.0000 24
GO:0055082 cellular chemical homeostasis 32/300 666/17913 0.0000 0.0000 32
GO:0050778 positive regulation of immune response 36/300 809/17913 0.0000 0.0000 36
GO:1903706 regulation of hemopoiesis 26/300 468/17913 0.0000 0.0000 26
GO:0098771 inorganic ion homeostasis 30/300 600/17913 0.0000 0.0000 30
GO:0007568 aging 21/300 318/17913 0.0000 0.0000 21
GO:1903047 mitotic cell cycle process 36/300 816/17913 0.0000 0.0000 36
GO:0030099 myeloid cell differentiation 24/300 411/17913 0.0000 0.0000 24
GO:0010243 response to organonitrogen compound 39/300 932/17913 0.0000 0.0000 39
GO:0000278 mitotic cell cycle 39/300 934/17913 0.0000 0.0000 39
GO:0016032 viral process 36/300 822/17913 0.0000 0.0000 36
GO:0007584 response to nutrient 17/300 215/17913 0.0000 0.0000 17
GO:0051186 cofactor metabolic process 28/300 543/17913 0.0000 0.0000 28
GO:0007159 leukocyte cell-cell adhesion 21/300 328/17913 0.0000 0.0000 21
GO:0055076 transition metal ion homeostasis 12/300 105/17913 0.0000 0.0000 12
GO:0002576 platelet degranulation 13/300 128/17913 0.0000 0.0000 13
GO:0033993 response to lipid 37/300 884/17913 0.0000 0.0000 37
GO:0051098 regulation of binding 22/300 368/17913 0.0000 0.0000 22
GO:0071222 cellular response to lipopolysaccharide 15/300 176/17913 0.0000 0.0000 15
GO:0050801 ion homeostasis 31/300 669/17913 0.0000 0.0000 31
GO:0050900 leukocyte migration 25/300 467/17913 0.0000 0.0000 25
GO:0071219 cellular response to molecule of bacterial origin 15/300 183/17913 0.0000 0.0000 15
GO:0002683 negative regulation of immune system process 24/300 451/17913 0.0000 0.0000 24
GO:0007346 regulation of mitotic cell cycle 29/300 622/17913 0.0000 0.0000 29
GO:0000122 negative regulation of transcription by RNA polymerase II 32/300 735/17913 0.0000 0.0000 32
GO:1905477 positive regulation of protein localization to membrane 12/300 120/17913 0.0000 0.0000 12
GO:0002637 regulation of immunoglobulin production 9/300 62/17913 0.0000 0.0000 9
GO:0008284 positive regulation of cell proliferation 37/300 931/17913 0.0000 0.0000 37
GO:0040008 regulation of growth 30/300 668/17913 0.0000 0.0000 30
GO:1901990 regulation of mitotic cell cycle phase transition 23/300 428/17913 0.0000 0.0000 23
GO:0045087 innate immune response 36/300 893/17913 0.0000 0.0000 36
GO:2000379 positive regulation of reactive oxygen species metabolic process 11/300 101/17913 0.0000 0.0001 11
GO:0055094 response to lipoprotein particle 7/300 33/17913 0.0000 0.0001 7
GO:0097193 intrinsic apoptotic signaling pathway 18/300 277/17913 0.0000 0.0001 18
GO:0044772 mitotic cell cycle phase transition 27/300 565/17913 0.0000 0.0001 27
GO:0055065 metal ion homeostasis 26/300 531/17913 0.0000 0.0001 26
GO:2000116 regulation of cysteine-type endopeptidase activity 16/300 222/17913 0.0000 0.0001 16
GO:1901987 regulation of cell cycle phase transition 24/300 464/17913 0.0000 0.0001 24
GO:0009991 response to extracellular stimulus 25/300 498/17913 0.0000 0.0001 25
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 15/300 196/17913 0.0000 0.0001 15
GO:0006954 inflammatory response 33/300 784/17913 0.0000 0.0001 33
GO:0045637 regulation of myeloid cell differentiation 17/300 250/17913 0.0000 0.0001 17
GO:0010507 negative regulation of autophagy 10/300 83/17913 0.0000 0.0001 10
GO:0006875 cellular metal ion homeostasis 24/300 467/17913 0.0000 0.0001 24
GO:0043302 positive regulation of leukocyte degranulation 6/300 22/17913 0.0000 0.0001 6
GO:0051338 regulation of transferase activity 36/300 903/17913 0.0000 0.0001 36
GO:0002699 positive regulation of immune effector process 15/300 198/17913 0.0000 0.0001 15
GO:0044770 cell cycle phase transition 28/300 609/17913 0.0000 0.0001 28
GO:0006914 autophagy 24/300 471/17913 0.0000 0.0001 24
GO:0061919 process utilizing autophagic mechanism 24/300 471/17913 0.0000 0.0001 24
GO:0071402 cellular response to lipoprotein particle stimulus 7/300 35/17913 0.0000 0.0001 7
GO:0002573 myeloid leukocyte differentiation 15/300 201/17913 0.0000 0.0001 15
GO:2001236 regulation of extrinsic apoptotic signaling pathway 13/300 151/17913 0.0000 0.0001 13
GO:0006979 response to oxidative stress 23/300 442/17913 0.0000 0.0001 23
GO:0051251 positive regulation of lymphocyte activation 17/300 258/17913 0.0000 0.0001 17
GO:0009895 negative regulation of catabolic process 18/300 288/17913 0.0000 0.0001 18
GO:0001819 positive regulation of cytokine production 23/300 446/17913 0.0000 0.0001 23
GO:0071216 cellular response to biotic stimulus 15/300 206/17913 0.0000 0.0001 15
GO:1900407 regulation of cellular response to oxidative stress 10/300 88/17913 0.0000 0.0001 10
GO:1901215 negative regulation of neuron death 15/300 207/17913 0.0000 0.0001 15
GO:0098609 cell-cell adhesion 32/300 771/17913 0.0000 0.0001 32
GO:1903708 positive regulation of hemopoiesis 14/300 182/17913 0.0000 0.0001 14
GO:0045785 positive regulation of cell adhesion 21/300 388/17913 0.0000 0.0001 21
GO:0032496 response to lipopolysaccharide 18/300 295/17913 0.0000 0.0001 18
GO:0070482 response to oxygen levels 21/300 389/17913 0.0000 0.0001 21
GO:0034599 cellular response to oxidative stress 18/300 296/17913 0.0000 0.0001 18
GO:1901652 response to peptide 24/300 491/17913 0.0000 0.0001 24
GO:0099132 ATP hydrolysis coupled cation transmembrane transport 8/300 54/17913 0.0000 0.0001 8
GO:0071901 negative regulation of protein serine/threonine kinase activity 12/300 136/17913 0.0000 0.0001 12
GO:0002685 regulation of leukocyte migration 14/300 186/17913 0.0000 0.0001 14
GO:0070661 leukocyte proliferation 17/300 270/17913 0.0000 0.0001 17
GO:1903039 positive regulation of leukocyte cell-cell adhesion 15/300 214/17913 0.0000 0.0001 15
GO:0051707 response to other organism 35/300 903/17913 0.0000 0.0001 35
GO:0043207 response to external biotic stimulus 35/300 905/17913 0.0000 0.0001 35
GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 6/300 26/17913 0.0000 0.0001 6
GO:0002764 immune response-regulating signaling pathway 27/300 603/17913 0.0000 0.0001 27
GO:0031330 negative regulation of cellular catabolic process 16/300 244/17913 0.0000 0.0001 16
GO:0071407 cellular response to organic cyclic compound 25/300 533/17913 0.0000 0.0001 25
GO:0030316 osteoclast differentiation 10/300 94/17913 0.0000 0.0001 10
GO:0006826 iron ion transport 8/300 56/17913 0.0000 0.0001 8
GO:0032943 mononuclear cell proliferation 16/300 246/17913 0.0000 0.0001 16
GO:0043086 negative regulation of catalytic activity 31/300 757/17913 0.0000 0.0001 31
GO:0052548 regulation of endopeptidase activity 20/300 370/17913 0.0000 0.0001 20
GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 7/300 41/17913 0.0000 0.0002 7
GO:0071396 cellular response to lipid 26/300 576/17913 0.0000 0.0002 26
GO:0043434 response to peptide hormone 21/300 404/17913 0.0000 0.0002 21
GO:0002237 response to molecule of bacterial origin 18/300 309/17913 0.0000 0.0002 18
GO:1902882 regulation of response to oxidative stress 10/300 97/17913 0.0000 0.0002 10
GO:0045089 positive regulation of innate immune response 20/300 373/17913 0.0000 0.0002 20
GO:1902107 positive regulation of leukocyte differentiation 12/300 143/17913 0.0000 0.0002 12
GO:0045088 regulation of innate immune response 22/300 440/17913 0.0000 0.0002 22
GO:0002697 regulation of immune effector process 22/300 441/17913 0.0000 0.0002 22
GO:0002377 immunoglobulin production 10/300 98/17913 0.0000 0.0002 10
GO:0034394 protein localization to cell surface 8/300 59/17913 0.0000 0.0002 8
GO:0010506 regulation of autophagy 18/300 314/17913 0.0000 0.0002 18
GO:0071900 regulation of protein serine/threonine kinase activity 23/300 479/17913 0.0000 0.0002 23
GO:0043300 regulation of leukocyte degranulation 7/300 43/17913 0.0000 0.0002 7
GO:0032930 positive regulation of superoxide anion generation 5/300 17/17913 0.0000 0.0002 5
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 10/300 100/17913 0.0000 0.0002 10
GO:0009611 response to wounding 28/300 665/17913 0.0000 0.0002 28
GO:0009607 response to biotic stimulus 35/300 938/17913 0.0000 0.0002 35
GO:0031589 cell-substrate adhesion 18/300 322/17913 0.0000 0.0002 18
GO:0071887 leukocyte apoptotic process 10/300 103/17913 0.0000 0.0002 10
GO:0043062 extracellular structure organization 20/300 387/17913 0.0000 0.0003 20
GO:0045921 positive regulation of exocytosis 9/300 82/17913 0.0000 0.0003 9
GO:2001235 positive regulation of apoptotic signaling pathway 13/300 178/17913 0.0000 0.0003 13
GO:0006897 endocytosis 28/300 675/17913 0.0000 0.0003 28
GO:0031400 negative regulation of protein modification process 26/300 602/17913 0.0000 0.0003 26
GO:1903037 regulation of leukocyte cell-cell adhesion 17/300 295/17913 0.0000 0.0003 17
GO:0009894 regulation of catabolic process 34/300 916/17913 0.0000 0.0003 34
GO:0051090 regulation of DNA-binding transcription factor activity 21/300 429/17913 0.0000 0.0003 21
GO:0051402 neuron apoptotic process 15/300 238/17913 0.0000 0.0003 15
GO:0050878 regulation of body fluid levels 23/300 499/17913 0.0000 0.0003 23
GO:0043523 regulation of neuron apoptotic process 14/300 210/17913 0.0000 0.0003 14
GO:0072593 reactive oxygen species metabolic process 16/300 269/17913 0.0000 0.0003 16
GO:0016049 cell growth 22/300 466/17913 0.0000 0.0003 22
GO:0031667 response to nutrient levels 22/300 466/17913 0.0000 0.0003 22
GO:0052547 regulation of peptidase activity 20/300 398/17913 0.0000 0.0003 20
GO:0051051 negative regulation of transport 23/300 502/17913 0.0000 0.0003 23
GO:0010564 regulation of cell cycle process 30/300 764/17913 0.0000 0.0004 30
GO:1903307 positive regulation of regulated secretory pathway 7/300 48/17913 0.0000 0.0004 7
GO:0002703 regulation of leukocyte mediated immunity 13/300 185/17913 0.0000 0.0004 13
GO:0097191 extrinsic apoptotic signaling pathway 14/300 213/17913 0.0000 0.0004 14
GO:0033002 muscle cell proliferation 15/300 243/17913 0.0000 0.0004 15
GO:0070663 regulation of leukocyte proliferation 14/300 214/17913 0.0000 0.0004 14
GO:0009117 nucleotide metabolic process 27/300 654/17913 0.0000 0.0004 27
GO:0046651 lymphocyte proliferation 15/300 244/17913 0.0000 0.0004 15
GO:0042113 B cell activation 14/300 215/17913 0.0000 0.0004 14
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 11/300 135/17913 0.0000 0.0004 11
GO:1902532 negative regulation of intracellular signal transduction 24/300 550/17913 0.0000 0.0005 24
GO:2001242 regulation of intrinsic apoptotic signaling pathway 12/300 163/17913 0.0000 0.0005 12
GO:0006753 nucleoside phosphate metabolic process 27/300 663/17913 0.0000 0.0005 27
GO:0032928 regulation of superoxide anion generation 5/300 21/17913 0.0000 0.0005 5
GO:0070848 response to growth factor 28/300 704/17913 0.0000 0.0005 28
GO:0002701 negative regulation of production of molecular mediator of immune response 6/300 35/17913 0.0000 0.0005 6
GO:0090322 regulation of superoxide metabolic process 6/300 35/17913 0.0000 0.0005 6
GO:0051272 positive regulation of cellular component movement 24/300 555/17913 0.0000 0.0005 24
GO:0022409 positive regulation of cell-cell adhesion 15/300 251/17913 0.0000 0.0005 15
GO:0045628 regulation of T-helper 2 cell differentiation 4/300 11/17913 0.0000 0.0005 4
GO:0036473 cell death in response to oxidative stress 9/300 92/17913 0.0000 0.0005 9
GO:0002312 B cell activation involved in immune response 8/300 71/17913 0.0000 0.0005 8
GO:0042100 B cell proliferation 8/300 71/17913 0.0000 0.0005 8
GO:0007249 I-kappaB kinase/NF-kappaB signaling 15/300 253/17913 0.0000 0.0006 15
GO:0002702 positive regulation of production of molecular mediator of immune response 9/300 93/17913 0.0000 0.0006 9
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 14/300 224/17913 0.0000 0.0006 14
GO:0098657 import into cell 29/300 751/17913 0.0000 0.0006 29
GO:0010742 macrophage derived foam cell differentiation 6/300 36/17913 0.0000 0.0006 6
GO:0015682 ferric iron transport 6/300 36/17913 0.0000 0.0006 6
GO:0033572 transferrin transport 6/300 36/17913 0.0000 0.0006 6
GO:0072512 trivalent inorganic cation transport 6/300 36/17913 0.0000 0.0006 6
GO:0090077 foam cell differentiation 6/300 36/17913 0.0000 0.0006 6
GO:0002705 positive regulation of leukocyte mediated immunity 10/300 117/17913 0.0000 0.0006 10
GO:0002761 regulation of myeloid leukocyte differentiation 10/300 117/17913 0.0000 0.0006 10
GO:0002218 activation of innate immune response 17/300 319/17913 0.0000 0.0006 17
GO:0050870 positive regulation of T cell activation 13/300 198/17913 0.0000 0.0006 13
GO:0051046 regulation of secretion 29/300 757/17913 0.0000 0.0006 29
GO:0002757 immune response-activating signal transduction 24/300 567/17913 0.0000 0.0007 24
GO:0022407 regulation of cell-cell adhesion 19/300 389/17913 0.0000 0.0007 19
GO:0030001 metal ion transport 30/300 800/17913 0.0000 0.0007 30
GO:0071404 cellular response to low-density lipoprotein particle stimulus 5/300 23/17913 0.0000 0.0007 5
GO:0032944 regulation of mononuclear cell proliferation 13/300 200/17913 0.0000 0.0007 13
GO:0048660 regulation of smooth muscle cell proliferation 12/300 172/17913 0.0000 0.0007 12
GO:0042089 cytokine biosynthetic process 10/300 120/17913 0.0000 0.0007 10
GO:0051101 regulation of DNA binding 10/300 120/17913 0.0000 0.0007 10
GO:0071888 macrophage apoptotic process 4/300 12/17913 0.0000 0.0007 4
GO:2000145 regulation of cell motility 34/300 966/17913 0.0000 0.0007 34
GO:1903201 regulation of oxidative stress-induced cell death 8/300 75/17913 0.0000 0.0007 8
GO:0031347 regulation of defense response 32/300 885/17913 0.0000 0.0007 32
GO:0042107 cytokine metabolic process 10/300 121/17913 0.0000 0.0007 10
GO:0007167 enzyme linked receptor protein signaling pathway 34/300 968/17913 0.0000 0.0007 34
GO:0048659 smooth muscle cell proliferation 12/300 174/17913 0.0000 0.0007 12
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 14/300 232/17913 0.0000 0.0008 14
GO:0043408 regulation of MAPK cascade 27/300 689/17913 0.0000 0.0008 27
GO:0043549 regulation of kinase activity 30/300 808/17913 0.0000 0.0008 30
GO:0071375 cellular response to peptide hormone stimulus 16/300 297/17913 0.0000 0.0008 16
GO:0006879 cellular iron ion homeostasis 7/300 57/17913 0.0000 0.0009 7
GO:0045859 regulation of protein kinase activity 28/300 733/17913 0.0000 0.0009 28
GO:0043112 receptor metabolic process 12/300 177/17913 0.0000 0.0009 12
GO:1901653 cellular response to peptide 18/300 364/17913 0.0000 0.0009 18
GO:0002758 innate immune response-activating signal transduction 16/300 298/17913 0.0000 0.0009 16
GO:0002819 regulation of adaptive immune response 11/300 150/17913 0.0000 0.0009 11
GO:0010959 regulation of metal ion transport 18/300 365/17913 0.0000 0.0009 18
GO:0036293 response to decreased oxygen levels 18/300 365/17913 0.0000 0.0009 18
GO:1902105 regulation of leukocyte differentiation 15/300 267/17913 0.0000 0.0009 15
GO:0051170 import into nucleus 10/300 125/17913 0.0000 0.0009 10
GO:0006732 coenzyme metabolic process 18/300 366/17913 0.0000 0.0009 18
GO:0048661 positive regulation of smooth muscle cell proliferation 9/300 101/17913 0.0000 0.0009 9
GO:1903827 regulation of cellular protein localization 22/300 509/17913 0.0001 0.0009 22
GO:0002719 negative regulation of cytokine production involved in immune response 5/300 25/17913 0.0001 0.0009 5
GO:0015991 ATP hydrolysis coupled proton transport 5/300 25/17913 0.0001 0.0009 5
GO:0030198 extracellular matrix organization 17/300 334/17913 0.0001 0.0009 17
GO:0055086 nucleobase-containing small molecule metabolic process 28/300 740/17913 0.0001 0.0009 28
GO:0031623 receptor internalization 9/300 102/17913 0.0001 0.0010 9
GO:0060341 regulation of cellular localization 31/300 863/17913 0.0001 0.0010 31
GO:0071346 cellular response to interferon-gamma 11/300 153/17913 0.0001 0.0010 11
GO:0031349 positive regulation of defense response 22/300 512/17913 0.0001 0.0010 22
GO:0007599 hemostasis 17/300 336/17913 0.0001 0.0010 17
GO:0051403 stress-activated MAPK cascade 15/300 271/17913 0.0001 0.0010 15
GO:1903530 regulation of secretion by cell 27/300 703/17913 0.0001 0.0010 27
GO:1905475 regulation of protein localization to membrane 12/300 181/17913 0.0001 0.0010 12
GO:0030334 regulation of cell migration 32/300 906/17913 0.0001 0.0010 32
GO:0009617 response to bacterium 24/300 588/17913 0.0001 0.0010 24
GO:0043536 positive regulation of blood vessel endothelial cell migration 8/300 80/17913 0.0001 0.0010 8
GO:0006911 phagocytosis, engulfment 6/300 41/17913 0.0001 0.0010 6
GO:0051348 negative regulation of transferase activity 15/300 272/17913 0.0001 0.0010 15
GO:0006606 protein import into nucleus 9/300 103/17913 0.0001 0.0010 9
GO:0048872 homeostasis of number of cells 14/300 241/17913 0.0001 0.0010 14
GO:0043534 blood vessel endothelial cell migration 12/300 182/17913 0.0001 0.0010 12
GO:0042110 T cell activation 20/300 443/17913 0.0001 0.0010 20
GO:0030335 positive regulation of cell migration 22/300 516/17913 0.0001 0.0010 22
GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 7/300 60/17913 0.0001 0.0010 7
GO:0016444 somatic cell DNA recombination 7/300 60/17913 0.0001 0.0010 7
GO:0060759 regulation of response to cytokine stimulus 12/300 183/17913 0.0001 0.0010 12
GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient 5/300 26/17913 0.0001 0.0010 5
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 26/300 669/17913 0.0001 0.0010 26
GO:0050863 regulation of T cell activation 16/300 307/17913 0.0001 0.0011 16
GO:0033673 negative regulation of kinase activity 14/300 244/17913 0.0001 0.0011 14
GO:0045926 negative regulation of growth 14/300 244/17913 0.0001 0.0011 14
GO:0051924 regulation of calcium ion transport 14/300 244/17913 0.0001 0.0011 14
GO:0006974 cellular response to DNA damage stimulus 29/300 791/17913 0.0001 0.0011 29
GO:0002523 leukocyte migration involved in inflammatory response 4/300 14/17913 0.0001 0.0011 4
GO:0045064 T-helper 2 cell differentiation 4/300 14/17913 0.0001 0.0011 4
GO:0010389 regulation of G2/M transition of mitotic cell cycle 12/300 185/17913 0.0001 0.0011 12
GO:0080135 regulation of cellular response to stress 27/300 713/17913 0.0001 0.0011 27
GO:0071363 cellular response to growth factor stimulus 26/300 674/17913 0.0001 0.0011 26
GO:0031098 stress-activated protein kinase signaling cascade 15/300 278/17913 0.0001 0.0012 15
GO:0002718 regulation of cytokine production involved in immune response 8/300 83/17913 0.0001 0.0012 8
GO:0099131 ATP hydrolysis coupled ion transmembrane transport 5/300 27/17913 0.0001 0.0012 5
GO:0070542 response to fatty acid 8/300 85/17913 0.0001 0.0014 8
GO:0002467 germinal center formation 4/300 15/17913 0.0001 0.0014 4
GO:0090662 ATP hydrolysis coupled transmembrane transport 5/300 28/17913 0.0001 0.0014 5
GO:0051100 negative regulation of binding 11/300 162/17913 0.0001 0.0014 11
GO:0002253 activation of immune response 25/300 647/17913 0.0001 0.0015 25
GO:0032602 chemokine production 8/300 86/17913 0.0001 0.0015 8
GO:0048145 regulation of fibroblast proliferation 8/300 86/17913 0.0001 0.0015 8
GO:0040017 positive regulation of locomotion 23/300 570/17913 0.0001 0.0015 23
GO:0042035 regulation of cytokine biosynthetic process 9/300 110/17913 0.0001 0.0015 9
GO:0050864 regulation of B cell activation 9/300 110/17913 0.0001 0.0015 9
GO:0071675 regulation of mononuclear cell migration 6/300 45/17913 0.0001 0.0015 6
GO:0006469 negative regulation of protein kinase activity 13/300 222/17913 0.0001 0.0015 13
GO:0051235 maintenance of location 15/300 286/17913 0.0001 0.0015 15
GO:0071466 cellular response to xenobiotic stimulus 11/300 164/17913 0.0001 0.0015 11
GO:0048144 fibroblast proliferation 8/300 87/17913 0.0001 0.0016 8
GO:0045936 negative regulation of phosphate metabolic process 23/300 573/17913 0.0001 0.0016 23
GO:0009411 response to UV 10/300 137/17913 0.0001 0.0016 10
GO:0032880 regulation of protein localization 33/300 979/17913 0.0001 0.0016 33
GO:0010563 negative regulation of phosphorus metabolic process 23/300 574/17913 0.0001 0.0016 23
GO:0071241 cellular response to inorganic substance 12/300 194/17913 0.0001 0.0016 12
GO:2000377 regulation of reactive oxygen species metabolic process 12/300 194/17913 0.0001 0.0016 12
GO:0044843 cell cycle G1/S phase transition 15/300 288/17913 0.0001 0.0016 15
GO:0031329 regulation of cellular catabolic process 29/300 814/17913 0.0001 0.0016 29
GO:0016241 regulation of macroautophagy 11/300 166/17913 0.0001 0.0017 11
GO:0097067 cellular response to thyroid hormone stimulus 4/300 16/17913 0.0001 0.0017 4
GO:2000147 positive regulation of cell motility 22/300 540/17913 0.0001 0.0017 22
GO:0071248 cellular response to metal ion 11/300 167/17913 0.0001 0.0017 11
GO:0030098 lymphocyte differentiation 16/300 325/17913 0.0001 0.0018 16
GO:0002200 somatic diversification of immune receptors 7/300 67/17913 0.0001 0.0018 7
GO:0010743 regulation of macrophage derived foam cell differentiation 5/300 30/17913 0.0001 0.0018 5
GO:0061082 myeloid leukocyte cytokine production 5/300 30/17913 0.0001 0.0018 5
GO:1901699 cellular response to nitrogen compound 24/300 620/17913 0.0001 0.0018 24
GO:0045639 positive regulation of myeloid cell differentiation 8/300 90/17913 0.0001 0.0019 8
GO:0001934 positive regulation of protein phosphorylation 31/300 907/17913 0.0001 0.0019 31
GO:0050670 regulation of lymphocyte proliferation 12/300 199/17913 0.0001 0.0019 12
GO:0000041 transition metal ion transport 8/300 91/17913 0.0001 0.0020 8
GO:0060333 interferon-gamma-mediated signaling pathway 8/300 91/17913 0.0001 0.0020 8
GO:0042327 positive regulation of phosphorylation 32/300 955/17913 0.0002 0.0021 32
GO:0010744 positive regulation of macrophage derived foam cell differentiation 4/300 17/17913 0.0002 0.0021 4
GO:0007596 blood coagulation 16/300 331/17913 0.0002 0.0021 16
GO:0042060 wound healing 22/300 550/17913 0.0002 0.0021 22
GO:0019216 regulation of lipid metabolic process 18/300 402/17913 0.0002 0.0022 18
GO:1902749 regulation of cell cycle G2/M phase transition 12/300 202/17913 0.0002 0.0022 12
GO:0006935 chemotaxis 22/300 551/17913 0.0002 0.0022 22
GO:0016447 somatic recombination of immunoglobulin gene segments 6/300 49/17913 0.0002 0.0022 6
GO:0034341 response to interferon-gamma 11/300 173/17913 0.0002 0.0022 11
GO:0051897 positive regulation of protein kinase B signaling 11/300 173/17913 0.0002 0.0022 11
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 9/300 118/17913 0.0002 0.0022 9
GO:0042330 taxis 22/300 553/17913 0.0002 0.0023 22
GO:0045597 positive regulation of cell differentiation 32/300 962/17913 0.0002 0.0023 32
GO:0033028 myeloid cell apoptotic process 5/300 32/17913 0.0002 0.0024 5
GO:0006259 DNA metabolic process 32/300 964/17913 0.0002 0.0024 32
GO:0045851 pH reduction 6/300 50/17913 0.0002 0.0024 6
GO:0099024 plasma membrane invagination 6/300 50/17913 0.0002 0.0024 6
GO:1905517 macrophage migration 6/300 50/17913 0.0002 0.0024 6
GO:0007229 integrin-mediated signaling pathway 8/300 94/17913 0.0002 0.0024 8
GO:0060627 regulation of vesicle-mediated transport 20/300 480/17913 0.0002 0.0024 20
GO:0000082 G1/S transition of mitotic cell cycle 14/300 269/17913 0.0002 0.0024 14
GO:0002224 toll-like receptor signaling pathway 10/300 147/17913 0.0002 0.0025 10
GO:0050817 coagulation 16/300 337/17913 0.0002 0.0025 16
GO:0033273 response to vitamin 8/300 95/17913 0.0002 0.0025 8
GO:0009410 response to xenobiotic stimulus 14/300 270/17913 0.0002 0.0025 14
GO:0006882 cellular zinc ion homeostasis 4/300 18/17913 0.0002 0.0025 4
GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 4/300 18/17913 0.0002 0.0025 4
GO:0051047 positive regulation of secretion 18/300 409/17913 0.0002 0.0025 18
GO:0002712 regulation of B cell mediated immunity 6/300 51/17913 0.0002 0.0026 6
GO:0002889 regulation of immunoglobulin mediated immune response 6/300 51/17913 0.0002 0.0026 6
GO:0002687 positive regulation of leukocyte migration 9/300 121/17913 0.0002 0.0026 9
GO:0016242 negative regulation of macroautophagy 5/300 33/17913 0.0002 0.0026 5
GO:0042554 superoxide anion generation 5/300 33/17913 0.0002 0.0026 5
GO:0045191 regulation of isotype switching 5/300 33/17913 0.0002 0.0026 5
GO:0097242 amyloid-beta clearance 5/300 33/17913 0.0002 0.0026 5
GO:0051169 nuclear transport 15/300 305/17913 0.0002 0.0026 15
GO:0048545 response to steroid hormone 17/300 375/17913 0.0002 0.0026 17
GO:0016236 macroautophagy 14/300 272/17913 0.0002 0.0026 14
GO:0040013 negative regulation of locomotion 17/300 377/17913 0.0002 0.0028 17
GO:0001909 leukocyte mediated cytotoxicity 8/300 97/17913 0.0002 0.0028 8
GO:0006909 phagocytosis 15/300 308/17913 0.0002 0.0028 15
GO:0045930 negative regulation of mitotic cell cycle 15/300 308/17913 0.0002 0.0028 15
GO:0043542 endothelial cell migration 14/300 275/17913 0.0002 0.0029 14
GO:0055072 iron ion homeostasis 7/300 74/17913 0.0002 0.0029 7
GO:0006163 purine nucleotide metabolic process 21/300 528/17913 0.0002 0.0029 21
GO:0051099 positive regulation of binding 11/300 181/17913 0.0002 0.0030 11
GO:0070838 divalent metal ion transport 19/300 454/17913 0.0002 0.0030 19
GO:0005996 monosaccharide metabolic process 14/300 277/17913 0.0003 0.0031 14
GO:0042326 negative regulation of phosphorylation 19/300 455/17913 0.0003 0.0031 19
GO:0002763 positive regulation of myeloid leukocyte differentiation 6/300 54/17913 0.0003 0.0033 6
GO:1903078 positive regulation of protein localization to plasma membrane 6/300 54/17913 0.0003 0.0033 6
GO:0046822 regulation of nucleocytoplasmic transport 8/300 100/17913 0.0003 0.0033 8
GO:0072511 divalent inorganic cation transport 19/300 458/17913 0.0003 0.0033 19
GO:0006164 purine nucleotide biosynthetic process 14/300 280/17913 0.0003 0.0034 14
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 10/300 155/17913 0.0003 0.0034 10
GO:0002367 cytokine production involved in immune response 8/300 101/17913 0.0003 0.0035 8
GO:0033194 response to hydroperoxide 4/300 20/17913 0.0003 0.0035 4
GO:0055069 zinc ion homeostasis 4/300 20/17913 0.0003 0.0035 4
GO:0071636 positive regulation of transforming growth factor beta production 4/300 20/17913 0.0003 0.0035 4
GO:0009636 response to toxic substance 20/300 499/17913 0.0003 0.0035 20
GO:0034109 homotypic cell-cell adhesion 7/300 77/17913 0.0003 0.0035 7
GO:0016445 somatic diversification of immunoglobulins 6/300 55/17913 0.0003 0.0035 6
GO:0031663 lipopolysaccharide-mediated signaling pathway 6/300 55/17913 0.0003 0.0035 6
GO:0042306 regulation of protein import into nucleus 6/300 55/17913 0.0003 0.0035 6
GO:0008286 insulin receptor signaling pathway 9/300 128/17913 0.0003 0.0036 9
GO:0032355 response to estradiol 9/300 128/17913 0.0003 0.0036 9
GO:1905521 regulation of macrophage migration 5/300 36/17913 0.0003 0.0036 5
GO:1903829 positive regulation of cellular protein localization 15/300 318/17913 0.0003 0.0037 15
GO:0017157 regulation of exocytosis 11/300 187/17913 0.0003 0.0037 11
GO:0010595 positive regulation of endothelial cell migration 9/300 129/17913 0.0003 0.0037 9
GO:0022617 extracellular matrix disassembly 7/300 78/17913 0.0003 0.0038 7
GO:0001666 response to hypoxia 16/300 354/17913 0.0003 0.0038 16
GO:0010631 epithelial cell migration 16/300 354/17913 0.0003 0.0038 16
GO:1903202 negative regulation of oxidative stress-induced cell death 6/300 56/17913 0.0003 0.0038 6
GO:0043535 regulation of blood vessel endothelial cell migration 10/300 158/17913 0.0003 0.0038 10
GO:0048524 positive regulation of viral process 8/300 103/17913 0.0003 0.0038 8
GO:0032868 response to insulin 13/300 252/17913 0.0003 0.0039 13
GO:0030212 hyaluronan metabolic process 5/300 37/17913 0.0004 0.0040 5
GO:0032101 regulation of response to external stimulus 29/300 873/17913 0.0004 0.0040 29
GO:0090132 epithelium migration 16/300 357/17913 0.0004 0.0040 16
GO:0090087 regulation of peptide transport 25/300 706/17913 0.0004 0.0041 25
GO:0006925 inflammatory cell apoptotic process 4/300 21/17913 0.0004 0.0041 4
GO:0046686 response to cadmium ion 6/300 57/17913 0.0004 0.0041 6
GO:1900408 negative regulation of cellular response to oxidative stress 6/300 57/17913 0.0004 0.0041 6
GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 6/300 57/17913 0.0004 0.0041 6
GO:0006886 intracellular protein transport 28/300 833/17913 0.0004 0.0041 28
GO:0017144 drug metabolic process 27/300 792/17913 0.0004 0.0042 27
GO:0071706 tumor necrosis factor superfamily cytokine production 10/300 161/17913 0.0004 0.0043 10
GO:0001558 regulation of cell growth 17/300 396/17913 0.0004 0.0043 17
GO:0009165 nucleotide biosynthetic process 16/300 360/17913 0.0004 0.0043 16
GO:0010324 membrane invagination 6/300 58/17913 0.0004 0.0044 6
GO:1904589 regulation of protein import 6/300 58/17913 0.0004 0.0044 6
GO:0050851 antigen receptor-mediated signaling pathway 12/300 224/17913 0.0004 0.0045 12
GO:0072522 purine-containing compound biosynthetic process 14/300 291/17913 0.0004 0.0045 14
GO:0035690 cellular response to drug 16/300 362/17913 0.0004 0.0045 16
GO:0090130 tissue migration 16/300 363/17913 0.0004 0.0047 16
GO:1990748 cellular detoxification 8/300 107/17913 0.0004 0.0047 8
GO:0016051 carbohydrate biosynthetic process 11/300 194/17913 0.0004 0.0047 11
GO:0000715 nucleotide-excision repair, DNA damage recognition 4/300 22/17913 0.0004 0.0047 4
GO:1902883 negative regulation of response to oxidative stress 6/300 59/17913 0.0004 0.0048 6
GO:2001056 positive regulation of cysteine-type endopeptidase activity 9/300 135/17913 0.0005 0.0048 9
GO:1901293 nucleoside phosphate biosynthetic process 16/300 365/17913 0.0005 0.0049 16
GO:0051223 regulation of protein transport 24/300 677/17913 0.0005 0.0050 24
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 14/300 295/17913 0.0005 0.0050 14
GO:0002706 regulation of lymphocyte mediated immunity 9/300 136/17913 0.0005 0.0050 9
GO:1903305 regulation of regulated secretory pathway 9/300 136/17913 0.0005 0.0050 9
GO:0045582 positive regulation of T cell differentiation 7/300 83/17913 0.0005 0.0050 7
GO:0050727 regulation of inflammatory response 19/300 479/17913 0.0005 0.0051 19
GO:0032869 cellular response to insulin stimulus 11/300 197/17913 0.0005 0.0052 11
GO:0007417 central nervous system development 30/300 935/17913 0.0005 0.0052 30
GO:0071417 cellular response to organonitrogen compound 21/300 559/17913 0.0005 0.0052 21
GO:0070201 regulation of establishment of protein localization 25/300 723/17913 0.0005 0.0053 25
GO:0072521 purine-containing compound metabolic process 21/300 560/17913 0.0005 0.0053 21
GO:0071621 granulocyte chemotaxis 7/300 84/17913 0.0005 0.0053 7
GO:0071677 positive regulation of mononuclear cell migration 4/300 23/17913 0.0005 0.0055 4
GO:1904377 positive regulation of protein localization to cell periphery 6/300 61/17913 0.0005 0.0055 6
GO:0030278 regulation of ossification 11/300 199/17913 0.0005 0.0056 11
GO:0006898 receptor-mediated endocytosis 14/300 301/17913 0.0006 0.0059 14
GO:0002639 positive regulation of immunoglobulin production 5/300 41/17913 0.0006 0.0059 5
GO:0032623 interleukin-2 production 6/300 62/17913 0.0006 0.0060 6
GO:0017038 protein import 9/300 140/17913 0.0006 0.0060 9
GO:0061024 membrane organization 25/300 730/17913 0.0006 0.0060 25
GO:0098655 cation transmembrane transport 25/300 730/17913 0.0006 0.0060 25
GO:0001959 regulation of cytokine-mediated signaling pathway 10/300 170/17913 0.0006 0.0060 10
GO:0097529 myeloid leukocyte migration 10/300 170/17913 0.0006 0.0060 10
GO:0006913 nucleocytoplasmic transport 14/300 302/17913 0.0006 0.0060 14
GO:0072507 divalent inorganic cation homeostasis 17/300 412/17913 0.0006 0.0061 17
GO:0043491 protein kinase B signaling 13/300 268/17913 0.0006 0.0061 13
GO:0000188 inactivation of MAPK activity 4/300 24/17913 0.0006 0.0062 4
GO:0043433 negative regulation of DNA-binding transcription factor activity 10/300 171/17913 0.0006 0.0062 10
GO:0051347 positive regulation of transferase activity 22/300 609/17913 0.0006 0.0062 22
GO:0030183 B cell differentiation 8/300 113/17913 0.0006 0.0062 8
GO:0098754 detoxification 8/300 113/17913 0.0006 0.0062 8
GO:0046637 regulation of alpha-beta T cell differentiation 6/300 63/17913 0.0006 0.0063 6
GO:0071277 cellular response to calcium ion 6/300 63/17913 0.0006 0.0063 6
GO:2000117 negative regulation of cysteine-type endopeptidase activity 7/300 87/17913 0.0006 0.0063 7
GO:0006816 calcium ion transport 17/300 415/17913 0.0007 0.0065 17
GO:0050792 regulation of viral process 11/300 204/17913 0.0007 0.0066 11
GO:0001933 negative regulation of protein phosphorylation 17/300 416/17913 0.0007 0.0067 17
GO:0002286 T cell activation involved in immune response 7/300 88/17913 0.0007 0.0067 7
GO:0010634 positive regulation of epithelial cell migration 10/300 173/17913 0.0007 0.0067 10
GO:0002323 natural killer cell activation involved in immune response 3/300 11/17913 0.0007 0.0067 3
GO:0019321 pentose metabolic process 3/300 11/17913 0.0007 0.0067 3
GO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus 3/300 11/17913 0.0007 0.0067 3
GO:0045670 regulation of osteoclast differentiation 6/300 64/17913 0.0007 0.0067 6
GO:0000086 G2/M transition of mitotic cell cycle 12/300 238/17913 0.0007 0.0068 12
GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 5/300 43/17913 0.0007 0.0070 5
GO:1903532 positive regulation of secretion by cell 16/300 381/17913 0.0007 0.0070 16
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 7/300 89/17913 0.0007 0.0070 7
GO:0045672 positive regulation of osteoclast differentiation 4/300 25/17913 0.0007 0.0070 4
GO:0097066 response to thyroid hormone 4/300 25/17913 0.0007 0.0070 4
GO:0006801 superoxide metabolic process 6/300 65/17913 0.0008 0.0072 6
GO:0051346 negative regulation of hydrolase activity 17/300 420/17913 0.0008 0.0072 17
GO:0006790 sulfur compound metabolic process 15/300 346/17913 0.0008 0.0073 15
GO:0051896 regulation of protein kinase B signaling 12/300 241/17913 0.0008 0.0074 12
GO:0097237 cellular response to toxic substance 12/300 241/17913 0.0008 0.0074 12
GO:1900180 regulation of protein localization to nucleus 8/300 117/17913 0.0008 0.0074 8
GO:0043524 negative regulation of neuron apoptotic process 9/300 146/17913 0.0008 0.0075 9
GO:0002708 positive regulation of lymphocyte mediated immunity 7/300 91/17913 0.0008 0.0078 7
GO:0007051 spindle organization 9/300 147/17913 0.0008 0.0078 9
GO:0010951 negative regulation of endopeptidase activity 11/300 210/17913 0.0009 0.0080 11
GO:2000679 positive regulation of transcription regulatory region DNA binding 4/300 26/17913 0.0009 0.0080 4
GO:0048589 developmental growth 22/300 624/17913 0.0009 0.0080 22
GO:1902600 proton transmembrane transport 9/300 148/17913 0.0009 0.0082 9
GO:0051928 positive regulation of calcium ion transport 8/300 119/17913 0.0009 0.0082 8
GO:0070227 lymphocyte apoptotic process 6/300 67/17913 0.0009 0.0082 6
GO:0001503 ossification 16/300 388/17913 0.0009 0.0082 16
GO:0051701 interaction with host 11/300 211/17913 0.0009 0.0082 11
GO:0043409 negative regulation of MAPK cascade 10/300 179/17913 0.0009 0.0082 10
GO:0032103 positive regulation of response to external stimulus 14/300 315/17913 0.0009 0.0083 14
GO:0072657 protein localization to membrane 20/300 545/17913 0.0009 0.0083 20
GO:0042308 negative regulation of protein import into nucleus 3/300 12/17913 0.0009 0.0083 3
GO:0051238 sequestering of metal ion 3/300 12/17913 0.0009 0.0083 3
GO:1904590 negative regulation of protein import 3/300 12/17913 0.0009 0.0083 3
GO:0045621 positive regulation of lymphocyte differentiation 7/300 93/17913 0.0010 0.0086 7
GO:0046364 monosaccharide biosynthetic process 7/300 93/17913 0.0010 0.0086 7
GO:1903076 regulation of protein localization to plasma membrane 7/300 93/17913 0.0010 0.0086 7
GO:0071674 mononuclear cell migration 6/300 68/17913 0.0010 0.0086 6
GO:0072503 cellular divalent inorganic cation homeostasis 16/300 392/17913 0.0010 0.0089 16
GO:0007160 cell-matrix adhesion 11/300 214/17913 0.0010 0.0089 11
GO:0032673 regulation of interleukin-4 production 4/300 27/17913 0.0010 0.0089 4
GO:0090068 positive regulation of cell cycle process 13/300 283/17913 0.0010 0.0090 13
GO:0002821 positive regulation of adaptive immune response 7/300 94/17913 0.0010 0.0090 7
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 7/300 94/17913 0.0010 0.0090 7
GO:0032680 regulation of tumor necrosis factor production 9/300 151/17913 0.0010 0.0090 9
GO:0042552 myelination 8/300 122/17913 0.0010 0.0092 8
GO:0046390 ribose phosphate biosynthetic process 13/300 284/17913 0.0010 0.0093 13
GO:0030168 platelet activation 9/300 152/17913 0.0011 0.0094 9
GO:0002768 immune response-regulating cell surface receptor signaling pathway 17/300 434/17913 0.0011 0.0095 17
GO:0030162 regulation of proteolysis 25/300 762/17913 0.0011 0.0095 25
GO:0002204 somatic recombination of immunoglobulin genes involved in immune response 5/300 47/17913 0.0011 0.0095 5
GO:0002208 somatic diversification of immunoglobulins involved in immune response 5/300 47/17913 0.0011 0.0095 5
GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 5/300 47/17913 0.0011 0.0095 5
GO:0045190 isotype switching 5/300 47/17913 0.0011 0.0095 5
GO:0045815 positive regulation of gene expression, epigenetic 5/300 47/17913 0.0011 0.0095 5
GO:0046638 positive regulation of alpha-beta T cell differentiation 5/300 47/17913 0.0011 0.0095 5
GO:0043393 regulation of protein binding 11/300 217/17913 0.0011 0.0097 11
GO:0050871 positive regulation of B cell activation 6/300 70/17913 0.0011 0.0097 6
GO:0042692 muscle cell differentiation 15/300 359/17913 0.0011 0.0097 15
GO:0036296 response to increased oxygen levels 4/300 28/17913 0.0011 0.0099 4
GO:0090383 phagosome acidification 4/300 28/17913 0.0011 0.0099 4
GO:0042177 negative regulation of protein catabolic process 8/300 124/17913 0.0012 0.0099 8